Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7745827

Cc1ccc(S(N)(=O)=O)c(CC(=O)O)c1.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.47
MAPT P10636 3/20 0.44
ALOX15 P16050 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PTGS2 P35354 5/20 0.43
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
ABCB11 O95342 1/20 0.39
PTGS1 P23219 1/20 0.39
PPARG P37231 1/20 0.39
NR1I3 Q14994 1/20 0.39
MPL P40238 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
AKR1B1 P15121 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6345635 0.85 SRC (0.53) SRCMAPTALOX15SMN1; SMN2PTGS2
SCHEMBL3491015 0.83 SRC (0.50) SRCMAPTALOX15SMN1; SMN2PTGS2
SCHEMBL1808146 0.80 PTGS2 (0.49) MAPTPTGS2CA12CA1CA2
SCHEMBL30069489 0.79 KDM4E (0.45) MAPTSMN1; SMN2PTGS2CA12CA1
SCHEMBL1559677 0.79 KDM4E (0.45) MAPTSMN1; SMN2PTGS2CA12CA1
SCHEMBL1808144 0.78 KDM4E (0.44) MAPTPTGS2CA12CA1CA2
SCHEMBL1806652 0.77 CA2 (0.41) MAPTPTGS2CA12CA1CA2
SCHEMBL4462790 0.76 CA2 (0.45) MAPTPTGS2CA12CA1CA2
SCHEMBL27745589 0.75 SRC (0.56) SRCMAPTALOX15SMN1; SMN2PTGS2
SCHEMBL17203591 0.75 ALDH1A1 (0.40) MAPTPTGS2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6290943-B1 WATER IN OIL EMULSION, HAIR CONDITIONERS UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-09-18 US disclosed
US-6235298-B1 LIQUID SHOWER GELS AND SHAMPOO, NONIONIC NATURAL GUM STABILIZER; SELECTION OF SURFACTANT SYSTEM AND THICKENER IS CRITICAL TO MULTIPLE EMULSION COMPOSITION NOT PHASESEPARATING UNILEVER HOME & PERSONAL CARE USA 2001-05-22 US disclosed
WO-2001028502-A1 STABLE MULTIPLE EMULSION COMPOSITION UNILEVER PLC (GB) 2001-04-26 WO disclosed