Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 15/20 | 0.54 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.50 |
| ▸ | RAC1 | P63000 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6347593 | 0.95 | TERT (0.53) | TERTDOT1LRAC1APAF1USP2 | |
| SCHEMBL6344443 | 0.85 | TERT (0.69) | TERTDOT1LAPAF1USP2POLB | |
| SCHEMBL5630261 | 0.83 | TERT (0.76) | TERTDOT1LRAC1 | |
| SCHEMBL6335955 | 0.82 | TERT (0.61) | TERTDOT1LAPAF1USP2POLB | |
| SCHEMBL4074842 | 0.76 | TERT (0.91) | TERTDOT1LKMT2A | |
| SCHEMBL6340164 | 0.76 | TERT (0.52) | TERTDOT1LAPAF1USP2POLB | |
| SCHEMBL6339837 | 0.74 | TERT (0.78) | TERTDOT1LKMT2A | |
| SCHEMBL4083568 | 0.73 | TERT (0.62) | TERTDOT1LRAC1 | |
| SCHEMBL4077093 | 0.73 | TERT (0.86) | TERTDOT1LKMT2A | |
| SCHEMBL4076918 | 0.72 | TERT (0.65) | TERTDOT1LRAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887873-B2 | Triazine derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2005-05-03 | — | — | US | claimed |