Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346417 | 0.98 | HDAC4 (0.40) | HDAC4HDAC2HDAC8TRPM4NUDT1 | |
| SCHEMBL6535325 | 0.82 | GRIN2D (0.59) | NPC1MAPTGRIN2DGRIN2AGRIN2B | |
| SCHEMBL4722085 | 0.81 | DRD2 (0.41) | DRD2SLC6A4MAPTMEN1KMT2A | |
| SCHEMBL27612187 | 0.81 | GRIN2D (0.57) | NPC1MAPTGRIN2DGRIN2AGRIN2B | |
| SCHEMBL4721556 | 0.80 | DRD2 (0.40) | DRD2SLC6A4KDM4EALDH1A1PTPN5 | |
| SCHEMBL4723104 | 0.78 | SLC6A4 (0.41) | DRD2SLC6A4MAPTMEN1KMT2A | |
| SCHEMBL27849970 | 0.76 | ALDH1A1 (0.39) | DRD2SLC6A4KDM4EALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL30487945 | 0.76 | HSP90AB1 (0.39) | DRD2SLC6A4CYP1A2 | |
| SCHEMBL497994 | 0.75 | SLC6A4 (0.56) | DRD2SLC6A4MEN1KMT2AALDH1A1 | |
| SCHEMBL29266777 | 0.75 | ALDH1A1 (0.38) | DRD2SLC6A4KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878659-B2 | Solid catalyst component for olefin polymerization and catalyst | TOHO TITANIUM CO., LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20040072681-A1 | Solid catalyst component for olefin polymerization and catalyst | TOHO TITANIUM CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1260524-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST | Toho Titanium Co., Ltd. (JP) | 2002-11-27 | — | — | EP | disclosed |