Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6347331 | 0.83 | HSPA5 (0.52) | HSPA5KEAP1POLBMAPTRAB9A | |
| SCHEMBL6279163 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2HSPA5KEAP1SLC7A5 | |
| SCHEMBL4799003 | 0.79 | KEAP1 (0.63) | GABRA1GABRB2HSPA5KEAP1SLC7A5 | |
| SCHEMBL30979255 | 0.78 | GABRA1 (0.69) | GABRA1GABRB2KEAP1SLC7A5ALOX5AP | |
| SCHEMBL13708433 | 0.78 | GABRA1 (0.69) | GABRA1GABRB2HSPA5KEAP1SLC7A5 | |
| SCHEMBL6338209 | 0.78 | SKP2 (0.50) | HSPA5KEAP1RAB9AMAPK1NPSR1 | |
| SCHEMBL3638974 | 0.78 | GABRA1 (0.63) | GABRA1GABRB2HSPA5KEAP1SLC7A5 | |
| SCHEMBL6338698 | 0.76 | HSPA5 (0.55) | HSPA5KEAP1MAPTNPSR1ALOX15 | |
| SCHEMBL12110846 | 0.76 | HSPA5 (0.59) | HSPA5KEAP1POLBMAPTRAB9A | |
| SCHEMBL13708432 | 0.75 | GABRA1 (0.59) | GABRA1GABRB2HSPA5KEAP1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960553-B2 | Heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20030186810-A1 | Heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD. | 2003-10-02 | — | — | US | disclosed |