SCHEMBL634588

SCHEMBL634588

CC(C)N(C(C)C)C(P)(CC#N)N(C(C)C)C(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27169563 0.77
SCHEMBL21496369 0.73
SCHEMBL2953440 0.71 CYP1A2 (0.30) CYP1A2MAPK1
SCHEMBL3453693 0.71
SCHEMBL7033913 0.70
SCHEMBL2112762 0.67
SCHEMBL8191873 0.65
SCHEMBL1060664 0.62
SCHEMBL634590 0.62
SCHEMBL634589 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2419478-B1 FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES LI COR INC (US) 2018-02-28 EP disclosed
EP-2630196-B1 CYANINE DYES AND THEIR CONJUGATES LI COR INC (US) 2017-09-06 EP disclosed
US-9408924-B2 Bioconjugates of cyanine dyes LI-COR, INC. (US) 2016-08-09 US disclosed
US-20150119553-A1 BIOCONJUGATES OF CYANINE DYES LI-COR, INC. 2015-04-30 US disclosed
US-8927719-B2 Cyanine dyes and their conjugates LI-COR, INC. (US) 2015-01-06 US disclosed
US-20130274452-A1 CYANINE DYES AND THEIR CONJUGATES MIDCAP FINANCIAL TRUST 2013-10-17 US disclosed
EP-2630196-A1 CYANINE DYES AND THEIR CONJUGATES LI-COR, INC. (US) 2013-08-28 EP disclosed
US-8481752-B2 Fluorescent imaging with substituted cyanine dyes LI-COR, INC. (US) 2013-07-09 US disclosed
WO-2012054749-A1 CYANINE DYES AND THEIR CONJUGATES LI-COR, INC. (US) 2012-04-26 WO disclosed
EP-2419478-A2 FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES LI-COR, INC. (US) 2012-02-22 EP disclosed
US-20100323389-A1 FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES LI-COR, INC. (US) 2010-12-23 US disclosed
WO-2010121163-A2 FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES LI-COR, INC. (US) 2010-10-21 WO disclosed
EP-1019887-B1 FLUORESCENT CYANINE DYES LI COR INC (US) 2003-04-02 EP disclosed
US-6027709-A BENZO(E)INDOLE-BASED DYES USEFUL AS REPORTER GROUPS FOR LABELING BIOMOECULES; SOLUBILITY RETAINED BY BIOMOLECULE; ATTACHMENT TO DNA, NUCLEOTIDES, PEPTIDES, HORMONES, ENZYMES ETC.; LASER ACTIVATION LI-COR INC. (US) 2000-02-22 US disclosed
US-5179200-A N4-(3-PHENYLPROPRIONYL)-2'-DEOXYCYTIDINE COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1993-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130274452-A1 CYANINE DYES AND THEIR CONJUGATES FCGR3B, QPCT, TIE1 CYP1A2 1397/4885MAPK1 2259/4885
US-20100323389-A1 FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES MSR1, TIE1, ALG1 CYP1A2 1991/4885MAPK1 2847/4885
US-20150119553-A1 BIOCONJUGATES OF CYANINE DYES FCGR3B, FCGR2A, HCCS CYP1A2 515/4885MAPK1 4120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.