Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.61 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5587185 | 0.91 | GABRA1 (0.73) | GABRA1GABRB2ELANECTSGKDM4E | |
| SCHEMBL31015759 | 0.83 | GABRA1 (0.52) | GABRA1GABRB2ELANECTSGKDM4E | |
| SCHEMBL2951870 | 0.81 | GABRA1 (0.55) | GABRA1GABRB2ELANECTSGKDM4E | |
| SCHEMBL1053654 | 0.80 | GABRA1 (0.79) | GABRA1GABRB2ELANECTSGHPGD | |
| SCHEMBL17878527 | 0.78 | GABRA1 (0.57) | GABRA1GABRB2ELANECTSGKDM4E | |
| SCHEMBL6343668 | 0.78 | TYR (0.43) | GABRA1GABRB2 | |
| SCHEMBL23387408 | 0.77 | GABRA1 (0.61) | GABRA1GABRB2ELANECTSGKDM4E | |
| SCHEMBL29079425 | 0.77 | GABRA1 (0.61) | GABRA1GABRB2ELANECTSGKDM4E | |
| SCHEMBL864085 | 0.76 | GABRA1 (1.00) | GABRA1GABRB2ELANECTSGKDM4E | |
| SCHEMBL276132 | 0.76 | GABRA1 (0.52) | GABRA1GABRB2ELANECTSGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878659-B2 | Solid catalyst component for olefin polymerization and catalyst | TOHO TITANIUM CO., LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20040072681-A1 | Solid catalyst component for olefin polymerization and catalyst | TOHO TITANIUM CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1260524-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST | Toho Titanium Co., Ltd. (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |