SCHEMBL6346325

SCHEMBL6346325

Oc1ccc2cc(F)cc(O)c2c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 6/20 0.42
RNASEH1 O60930 1/20 0.42
GPR35 Q9HC97 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 2/20 0.41
DNMT1 P26358 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
MCL1 Q07820 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
CDK2 P24941 1/20 0.39
CA9 Q16790 2/20 0.39
CA3 P07451 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20356048 0.79 MGAM (0.47) PTPN11RNASEH1GPR35ATG4BMEN1
SCHEMBL6348831 0.76 PTPN11 (0.41) PTPN11RNASEH1GPR35ATG4BMEN1
SCHEMBL6358383 0.76 PTPN11 (0.41) PTPN11RNASEH1GPR35ATG4BMEN1
SCHEMBL6355906 0.76 SELL (0.48) PTPN11RNASEH1GPR35ATG4BMEN1
SCHEMBL18940921 0.71 MGAM (0.44) PTPN11RNASEH1GPR35ATG4BMEN1
SCHEMBL6345593 0.71 PTPN22 (0.50) CA9CA3CA6CA5ACA14
SCHEMBL6346766 0.68 CA9 (0.55) ALDH1A1CDK2CA9CA3CA6
SCHEMBL6349397 0.67 CDK2 (0.69) MEN1ALDH1A1KMT2ADNMT1CACNA1B
SCHEMBL31037125 0.67 CDK2 (0.69) MEN1ALDH1A1KMT2ADNMT1CACNA1B
SCHEMBL5511592 0.67 CA9 (0.48) CA9CA3CA6CA5ACA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US disclosed
US-20040072681-A1 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2004-04-15 US disclosed
EP-1260524-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Titanium Co., Ltd. (JP) 2002-11-27 EP disclosed