SCHEMBL6349397

SCHEMBL6349397

Oc1ccc2cccc(O)c2c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 3/20 0.69
ALDH1A1 P00352 5/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
DNMT1 P26358 1/20 0.62
CACNA1B Q00975 1/20 0.62
APBA1 Q02410 1/20 0.62
MCL1 Q07820 1/20 0.62
APOBEC3G Q9HC16 1/20 0.62
HPGD P15428 5/20 0.52
HSD17B10 Q99714 5/20 0.52
ALOX15 P16050 4/20 0.52
RECQL P46063 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
LMNA P02545 2/20 0.52
ADAMTS4 O75173 1/20 0.52
EGFR P00533 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
FYN P06241 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037125 1.00 CDK2 (0.69) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL7915327 0.93 CDK2 (0.67) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL7126508 0.84 ALDH1A1 (0.59) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL8623653 0.83 ALDH1A1 (0.60) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL193772 0.82 CDK2 (1.00) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL29363189 0.81 ALDH1A1 (0.62) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL70219 0.81 ALDH1A1 (0.62) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL18068453 0.80 CDK2 (0.52) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL22444700 0.79 CDK2 (0.57) CDK2ALDH1A1MEN1KMT2ADNMT1
SCHEMBL2981975 0.79 CDK2 (0.57) CDK2ALDH1A1MEN1KMT2ADNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5597876-A CURING AGENT PROVIDES BETTER MECHANICAL PROPERTIES AT HIGH TEMPERATURE SHELL OIL COMPANY (US) 1997-01-28 US claimed
US-20230194990-A1 PHOTORESIST UNDERLAYER COMPOSITION U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-06-22 US disclosed
US-20230194990-A1 PHOTORESIST UNDERLAYER COMPOSITION U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-06-22 US disclosed
US-10793584-B2 Naphthobischalcogenadiazole derivative and production method therefor OSAKA UNIVERSITY (JP) 2020-10-06 US disclosed
US-20190337966-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR OSAKA UNIVERSITY (JP) 2019-11-07 US disclosed
EP-3564245-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR Osaka University (JP) 2019-11-06 EP disclosed
WO-2018123207-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR 国立大学法人大阪大学 2018-07-05 WO disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US disclosed
EP-1260524-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Titanium Co., Ltd. (JP) 2002-11-27 EP disclosed
EP-1218178-A1 AN ADHESION PROMOTING LAYER FOR USE WITH EPOXY PREPREGS Ga-Tek Inc. (US) 2002-07-03 EP disclosed
EP-0810249-B1 Thermosetting resin composition, electrically insulated coil, electric rotating machine and method for producing same HITACHI LTD (JP) 2001-11-07 EP disclosed
WO-2001019607-A1 AN ADHESION PROMOTING LAYER FOR USE WITH EPOXY PREPREGS GA-TEK INC. (US) 2001-03-22 WO disclosed
US-6117536-A MULTILAYER STRUCTURE COMPRISING PREPREG LAYER MADE FROM EPOXY RESIN AND NON-AMINE CURING AGENT, NITROGEN-CONTAINING SILANE ADHESION PROMOTING LAYER GA-TEK INC. (US) 2000-09-12 US disclosed
US-5982056-A STATOR OF ROTATING MACHINE HITACHI, LTD. (JP) 1999-11-09 US disclosed
EP-0720630-B1 EPOXY RESIN COMPOSITION SHELL INT RESEARCH (NL) 1999-03-17 EP disclosed
EP-0810249-A2 Thermosetting resin composition, electrically insulated coil, electric rotating machine and method for producing same HITACHI, LTD. (JP) 1997-12-03 EP disclosed
US-5597876-A CURING AGENT PROVIDES BETTER MECHANICAL PROPERTIES AT HIGH TEMPERATURE SHELL OIL COMPANY (US) 1997-01-28 US disclosed
EP-0682052-A1 Composition of epoxy resins based on condensed polynuclear aromatic compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793584-B2 Naphthobischalcogenadiazole derivative and production method therefor CYP24A1, CYP26B1, CYP21A2 CDK2 739/4885ALDH1A1 600/4885MEN1 260/4885
US-20190337966-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR CYP24A1, CYP26B1, CYP21A2 CDK2 739/4885ALDH1A1 600/4885MEN1 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.