SCHEMBL6345593

SCHEMBL6345593

Oc1ccc2cc(F)ccc2c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.50
LCK P06239 3/20 0.47
ESR1 P03372 4/20 0.43
ESR2 Q92731 4/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2A6 P11509 1/20 0.43
CDC42 P60953 2/20 0.41
RAC1 P63000 2/20 0.41
AMY1A P0DUB6 1/20 0.39
DAO P14920 2/20 0.39
NPC1 O15118 1/20 0.39
DDO Q99489 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6568133 0.83 CA3 (0.48) ESR1ESR2CA3CA6CA5A
SCHEMBL5367030 0.83 HSD17B1 (0.44) ESR1ESR2CA3CA6CA5A
SCHEMBL12760750 0.79 CYP1A2 (0.40) CA3CA6CA5ACA9CA14
SCHEMBL30574198 0.79 ESR1 (0.58) ESR1ESR2CA3CA6CA5A
SCHEMBL28237634 0.79 ESR1 (0.58) ESR1ESR2CA3CA6CA5A
SCHEMBL6346791 0.78 CA3 (0.48) ESR1ESR2CA3CA6CA5A
SCHEMBL3213734 0.77 PTPN22 (0.54) PTPN22LCKESR1ESR2CYP1A2
SCHEMBL29720904 0.77 PTPN22 (0.54) PTPN22LCKESR1ESR2CYP1A2
SCHEMBL12260024 0.76 CYP1A2 (0.55) CA3CA6CA5ACA9CA14
SCHEMBL18068463 0.76 PTPN22 (0.56) PTPN22LCKESR1ESR2CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US disclosed
US-20040072681-A1 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2004-04-15 US disclosed
EP-1260524-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Titanium Co., Ltd. (JP) 2002-11-27 EP disclosed