SCHEMBL6346597

SCHEMBL6346597

C=C(C)C(CCN1C(=O)c2cccc3c(OC)ccc(c23)C1=O)OO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.55
ALDH1A1 P00352 4/20 0.54
KMT2A Q03164 4/20 0.54
LMNA P02545 3/20 0.54
MAPT P10636 3/20 0.54
POLB P06746 3/20 0.54
HTT P42858 2/20 0.54
KDM4E B2RXH2 1/20 0.54
PABPC1 P11940 1/20 0.54
XBP1 P17861 1/20 0.54
NFKB1 P19838 1/20 0.54
SMARCA2 P51531 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
HDAC3 O15379 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
KEAP1 Q14145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6347671 0.83 HEXA (0.54) ALDH1A1KMT2AMAPTPOLBKDM4E
SCHEMBL12922803 0.81 ALDH1A1 (0.51) ALDH1A1MAPTHPGDSMN1; SMN2RAB9A
SCHEMBL21610449 0.79 PRMT1 (0.69) PRMT1ALDH1A1KMT2ALMNAMAPT
SCHEMBL9437172 0.77 PRMT1 (0.71) PRMT1ALDH1A1KMT2ALMNAMAPT
SCHEMBL6345868 0.77 PRMT1 (0.56) PRMT1ALDH1A1KMT2ALMNAMAPT
SCHEMBL12257025 0.76 HEXA (0.48) ALDH1A1KMT2ALMNAMAPTPOLB
SCHEMBL30534976 0.75 PRMT1 (0.68) PRMT1ALDH1A1KMT2ALMNAMAPT
SCHEMBL9437170 0.75 PRMT1 (0.68) PRMT1ALDH1A1KMT2ALMNAMAPT
SCHEMBL13288146 0.75 TERT (0.63) PRMT1ALDH1A1KMT2ALMNAMAPT
SCHEMBL10563912 0.75 PRMT1 (0.63) PRMT1ALDH1A1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173226-B2 Polymerizable compound , polyethylene glycol mono(meth)acrylate, a polystyrene oligomer having a methacryloyl group at one terminal, acrylic macromonomer imides FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed