SCHEMBL6347709

SCHEMBL6347709

CC(C)=CCCC(C)(O)C(=O)CO

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 8/20 0.47
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
CYP3A4 P08684 4/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
MAPK1 P28482 1/20 0.33
CHRNA7 P36544 1/20 0.33
STAT3 P40763 1/20 0.33
POLB P06746 1/20 0.33
HIF1A Q16665 1/20 0.33
EPAS1 Q99814 1/20 0.33
MAPT P10636 3/20 0.32
ALDH1A1 P00352 2/20 0.32
SQLE Q14534 1/20 0.32
UGT1A1 P22309 1/20 0.32
PTPN1 P18031 1/20 0.32
LMNA P02545 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1301267 1.00 ALOX15 (0.47) ALOX15KDM4EATMCYP3A4MEN1
SCHEMBL28123430 1.00 ALOX15 (0.47) ALOX15KDM4EATMCYP3A4MEN1
SCHEMBL4748771 0.81 ALOX15 (0.52) ALOX15KDM4EATMCYP3A4MEN1
SCHEMBL13648282 0.73
SCHEMBL26691671 0.72 ALOX15 (0.57) ALOX15CYP3A4MEN1KMT2AMAPK1
SCHEMBL583687 0.71 ALOX15 (0.60) ALOX15KDM4EATMCYP3A4MEN1
SCHEMBL5907126 0.70 ALOX15 (0.54) ALOX15CYP3A4MEN1KMT2AMAPK1
SCHEMBL14323431 0.70 ALOX15 (0.48) ALOX15KDM4EATMCYP3A4MEN1
SCHEMBL18102808 0.68 ALOX15 (0.52) ALOX15CYP3A4MEN1KMT2AMAPK1
SCHEMBL6436094 0.68 HMGCR (0.54) ALOX15KDM4EATMCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141964-A1 FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF EAST CHINA NORMAL UNIVERSITY (CN) 2018-05-24 US claimed
US-6958360-B2 Attractant pheromone for the Colorado potato beetle THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-10-25 US claimed
US-20030068352-A1 Attractant pheromone for the Colorado potato beetle AGRICULTURE, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF, THE 2003-04-10 US claimed
WO-2003026423-A1 ATTRACTANT PHEROMONE FOR THE COLORADO POTATO BEETLE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2003-04-03 WO claimed
US-10450331-B2 Functionalized cyanosilane and synthesis method and use thereof EAST CHINA NORMAL UNIVERSITY (CN) 2019-10-22 US disclosed
US-20180141964-A1 FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF EAST CHINA NORMAL UNIVERSITY (CN) 2018-05-24 US disclosed
CN-106365962-A 1,3-dihydroxy-3,7-dimethyl-6-octen-2-one synthesis method 华东师范大学 2017-02-01 CN disclosed
CN-106365962-A 1,3-dihydroxy-3,7-dimethyl-6-octen-2-one synthesis method 华东师范大学 2017-02-01 CN disclosed
US-6958360-B2 Attractant pheromone for the Colorado potato beetle THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-10-25 US disclosed
US-6958360-B2 Attractant pheromone for the Colorado potato beetle THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-10-25 US disclosed
US-20030068352-A1 Attractant pheromone for the Colorado potato beetle AGRICULTURE, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF, THE 2003-04-10 US disclosed
US-20030068352-A1 Attractant pheromone for the Colorado potato beetle AGRICULTURE, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF, THE 2003-04-10 US disclosed
WO-2003026423-A1 ATTRACTANT PHEROMONE FOR THE COLORADO POTATO BEETLE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2003-04-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141964-A1 FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF NCLN, PNN, MB ALOX15 4315/4885KDM4E 2353/4885ATM 532/4885
US-10450331-B2 Functionalized cyanosilane and synthesis method and use thereof NCLN, PNN, MB ALOX15 4315/4885KDM4E 2353/4885ATM 532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.