Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348150 | 1.00 | L3MBTL1 (0.40) | L3MBTL1PIK3CDRIPK1ALDH1A1LMNA | |
| SCHEMBL6346705 | 1.00 | L3MBTL1 (0.40) | L3MBTL1PIK3CDRIPK1ALDH1A1LMNA | |
| SCHEMBL6348102 | 0.89 | CA12 (0.36) | L3MBTL1PIK3CDALDH1A1 | |
| SCHEMBL6348100 | 0.89 | CA12 (0.36) | L3MBTL1PIK3CDALDH1A1 | |
| SCHEMBL6349771 | 0.89 | CA12 (0.36) | L3MBTL1PIK3CDALDH1A1 | |
| SCHEMBL6357399 | 0.89 | PKM (0.38) | L3MBTL1PIK3CDRIPK1ALDH1A1PLOD2 | |
| SCHEMBL6357403 | 0.89 | PKM (0.38) | L3MBTL1PIK3CDRIPK1ALDH1A1PLOD2 | |
| SCHEMBL6355704 | 0.89 | PKM (0.38) | L3MBTL1PIK3CDRIPK1ALDH1A1PLOD2 | |
| SCHEMBL6348428 | 0.83 | CMA1 (0.40) | ALDH1A1LMNACTSK | |
| SCHEMBL6348486 | 0.83 | ECE1 (0.43) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960575-B2 | For use as inhibitors of chymase | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040097496-A1 | Novel thiazine derivatives | SANTEN PHARMACEUTICAL CO.,LTD. (JP) | 2004-05-20 | — | — | US | disclosed |
| US-6713472-B1 | 2-OXO-1,2,3,4-TETRAHYDROPYRAZINE DERIVATIVES; CHYMASE INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097496-A1 | Novel thiazine derivatives | CMA1, TPSD1, HRH4 | L3MBTL1 3961/4885PIK3CD 4569/4885RIPK1 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.