Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.63 |
| ▸ | NSD2 | O96028 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17069809 | 0.82 | CDK2 (0.70) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL6349397 | 0.82 | CDK2 (0.69) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL31037125 | 0.82 | CDK2 (0.69) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7915327 | 0.80 | CDK2 (0.67) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL29419413 | 0.79 | CDK2 (0.66) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| Purpurogallin SCHEMBL2839450 | 0.79 | CDK2 (0.93) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL14399740 | 0.78 | CDK2 (0.64) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| Purpurogallin SCHEMBL29481120 | 0.78 | CDK2 (1.00) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| Purpurogallin SCHEMBL33853 | 0.78 | CDK2 (1.00) | CDK2ALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL344192 | 0.74 | ALDH1A1 (0.61) | CDK2ALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500186-A | — | — | 2012-01-05 | — | — | JP | claimed |
| US-20110123468-A1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2011-05-26 | — | — | US | claimed |
| EP-2296760-A2 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2011-03-23 | — | — | EP | claimed |
| WO-2009156324-A2 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2009-12-30 | — | — | WO | claimed |
| US-20240424043-A1 | COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASE COMPRISING ARALIA ELATA EXTRACT | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2024-12-26 | — | — | US | disclosed |
| US-20220125766-A1 | METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION | MAGGIES PEARL LLC (US) | 2022-04-28 | — | — | US | disclosed |
| US-20210386709-A1 | COMPOSITIONS AND METHODS FOR SUPPRESSING MSUT2 | US GOV VETERANS AFFAIRS (US) | 2021-12-16 | — | — | US | disclosed |
| US-11160794-B2 | Methods for treating congenital disorders of glycosylation | MAGGIE'S PEARL, LLC (US) | 2021-11-02 | — | — | US | disclosed |
| US-20210030721-A1 | METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION | PERLARA PBC | 2021-02-04 | — | — | US | disclosed |
| WO-2020040831-A1 | METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION | PERLARA PBC (US) | 2020-02-27 | — | — | WO | disclosed |
| US-9707417-B2 | Use of benzotropolone derivatives as UV absorbers and antioxidants and their use in sunscreens and/or cosmetic compositions | BASF SE (DE) | 2017-07-18 | — | — | US | disclosed |
| US-9527878-B2 | Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-12-27 | — | — | US | disclosed |
| US-20110123468-A1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2011-05-26 | — | — | US | disclosed |
| EP-2296760-A2 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2011-03-23 | — | — | EP | disclosed |
| US-20100137194-A1 | Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2010-06-03 | — | — | US | disclosed |
| US-20100137194-A1 | Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2010-06-03 | — | — | US | disclosed |
| WO-2009156324-A2 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2009-12-30 | — | — | WO | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-5681604-A | PLANT EXTRACTS; GREEN TEA, TANNIC ACID, EPICATECHIN GALLATE, GALLIC ACID CARBOHYDRATE REACTION PRODUCTS | DELAWARE, UNIVERSITY OF | 1997-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137194-A1 | Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism | SERPINE1, PLAT, SERPINB1 | CDK2 2422/4885ALDH1A1 918/4885HPGD 502/4885 |
| US-20240424043-A1 | COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASE COMPRISING ARALIA ELATA EXTRACT | PYGM, CPT1B, GYS1 | CDK2 3555/4885ALDH1A1 2901/4885HPGD 2981/4885 |
| US-11160794-B2 | Methods for treating congenital disorders of glycosylation | MAN1B1, MAN2B1, GAA | CDK2 4210/4885ALDH1A1 1692/4885HPGD 2760/4885 |
| US-20110123468-A1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | CBR3, SCO2, CBR1 | CDK2 359/4885ALDH1A1 690/4885HPGD 415/4885 |
| US-20210030721-A1 | METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION | MAN1B1, MAN2B1, GAA | CDK2 4210/4885ALDH1A1 1692/4885HPGD 2760/4885 |
| US-20220125766-A1 | METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION | MAN1B1, MAN2B1, GAA | CDK2 4210/4885ALDH1A1 1692/4885HPGD 2760/4885 |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | CCNK, CDK3, CCNO | CDK2 27/4885ALDH1A1 1982/4885HPGD 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.