Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30826334 | 0.98 | TDP1 (0.38) | TDP1CYP3A4ALDH1A1CYP2A6ADH1B | |
| SCHEMBL4972429 | 0.79 | CYP3A4 (0.43) | TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL1038657 | 0.76 | CYP3A4 (0.36) | TDP1CYP3A4ALDH1A1CYP2A6ADH1B | |
| SCHEMBL27893167 | 0.75 | CYP3A4 (0.39) | TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL381091 | 0.75 | CYP3A4 (0.39) | TDP1CYP3A4ALDH1A1ESR1ESR2 | |
| SCHEMBL8104110 | 0.75 | CYP3A4 (0.39) | TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL8154471 | 0.75 | CYP3A4 (0.39) | TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL10975182 | 0.75 | CYP3A4 (0.35) | TDP1CYP3A4 | |
| Formaldehyde SCHEMBL11418512 | 0.75 | CYP3A4 (0.35) | TDP1CYP3A4ALDH1A1LMNA | |
| Iodide SCHEMBL28416673 | 0.75 | CYP3A4 (0.35) | TDP1CYP3A4ALDH1A1CYP2A6ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135698-B | Process for producing cyclic polysiloxane | 信越化学工业株式会社 | 2024-04-26 | — | — | CN | disclosed |
| CN-115135698-A | Method for producing cyclic polysiloxane | 信越化学工业株式会社 | 2022-09-30 | — | — | CN | disclosed |
| CN-107709322-B | Tricyclic compounds as anticancer agents | 百时美施贵宝公司 | 2021-05-07 | — | — | CN | disclosed |
| US-9597673-B2 | Iron catalysts with unsymmetrical PNN'P ligands | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-03-21 | — | — | US | disclosed |
| CN-106165175-A | High molecular electrolyte composition and use its polyelectrolyte membrane, film electrode composite element and polymer electrolyte fuel cell | 东丽株式会社 | 2016-11-23 | — | — | CN | disclosed |
| US-20150151289-A1 | IRON CATALYSTS WITH UNSYMMETRICAL PNN'P LIGANDS | GOVERING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-06-04 | — | — | US | disclosed |
| US-20140243543-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2014-08-28 | — | — | US | disclosed |
| US-7642366-B2 | Phosphine ligands | HOFFMANN-LA ROCHE INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20090326253-A1 | NOVEL PHOSPHINE LIGANDS | IDING HANS | 2009-12-31 | — | — | US | disclosed |
| US-6963005-B2 | Compounds comprising phosphorus-containing metal complexes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-11-08 | — | — | US | disclosed |
| CN-1117115-C | Copper bromide polymer, its synthesis method and its application | INST OF CHEMISTRY HE NAN PROV (CN) | 2003-08-06 | — | — | CN | disclosed |
| CN-1072967-C | Uncomplexed cyclodextrin solutions for odor control or inanimate surface | PROCTER & GAMBLES CO (US) | 2001-10-17 | — | — | CN | disclosed |
| CN-1257859-A | Process for preparing 3-pentenic acid from allyl butenyl alcohol or ester using nickel catalyst | DU PONT (US) | 2000-06-28 | — | — | CN | disclosed |
| US-6015923-A | REACTING ALCOHOL OR ESTER WITH CARBON MONOXIDE IN PRESENCE OF NICKEL AND IODIDE SOURCE IN CARBOXYLIC ACID SOLVENT UNDER SPECIFIED CONDITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-01-18 | — | — | US | disclosed |
| CN-1161002-A | Composition for reducing malodor impression on inanimate surfaces | PROCTER & GAMBLE (US) | 1997-10-01 | — | — | CN | disclosed |
| CN-1159762-A | Uncomplexed cyclodextrin solutions for odor control or inanimate surface | PROCTER & GAMBLE (US) | 1997-09-17 | — | — | CN | disclosed |
| EP-0340391-B1 | 1,4-Disubstituted-2,3,4,6-tetrahydroxy-1,4-diphosphorinane and their oxides or sulfides | CANADA CYANAMID (CA) | 1994-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150151289-A1 | IRON CATALYSTS WITH UNSYMMETRICAL PNN'P LIGANDS | PNN, NCL, IDH2 | TDP1 2154/4885CYP3A4 1727/4885ALDH1A1 1384/4885 |
| US-20090326253-A1 | NOVEL PHOSPHINE LIGANDS | PRMT8, GRB7, STK38L | TDP1 4580/4885CYP3A4 1963/4885ALDH1A1 4347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.