Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.76 |
| ▸ | DRD4 | P21917 | 12/20 | 0.69 |
| ▸ | DRD2 | P14416 | 7/20 | 0.69 |
| ▸ | DRD3 | P35462 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HTR2C | P28335 | 3/20 | 0.59 |
| ▸ | HTR7 | P34969 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352777 | 0.91 | HTR1A (0.76) | HTR1ADRD4DRD2DRD3HPGD | |
| SCHEMBL6351416 | 0.87 | HTR1A (1.00) | HTR1ADRD4DRD2DRD3HTR2A | |
| SCHEMBL6357059 | 0.86 | HTR1A (0.72) | HTR1ADRD4DRD2DRD3HTR2A | |
| SCHEMBL6351568 | 0.86 | HTR1A (0.76) | HTR1ADRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL6359034 | 0.86 | HTR1A (0.76) | HTR1ADRD4DRD2DRD3HPGD | |
| SCHEMBL6359405 | 0.84 | DRD4 (0.79) | DRD4DRD2DRD3 | |
| SCHEMBL6359407 | 0.84 | DRD4 (0.79) | DRD4DRD2DRD3 | |
| SCHEMBL6346874 | 0.84 | DRD4 (0.71) | HTR1ADRD4DRD2DRD3HTR2A | |
| SCHEMBL6352385 | 0.84 | HTR1A (0.71) | HTR1ADRD4DRD2DRD3HTR2A | |
| SCHEMBL4006809 | 0.84 | DRD4 (0.76) | DRD4DRD2DRD3HPGDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | HTR1A 871/4885DRD4 1272/4885DRD2 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.