SCHEMBL634976

SCHEMBL634976

OP(O)(=S)Oc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.64
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
ALDH1A1 P00352 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAPT P10636 1/20 0.58
ALOX15 P16050 1/20 0.58
TSHR P16473 1/20 0.58
ALOX12 P18054 1/20 0.58
MAPK1 P28482 1/20 0.58
ATM Q13315 1/20 0.58
HSD17B10 Q99714 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
F2 P00734 1/20 0.30
F10 P00742 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11430342 0.81 TDP1 (0.44) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL16506502 0.81 TDP1 (0.54) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL28328185 0.79 TDP1 (0.73) TDP1MEN1KMT2AALDH1A1CYP3A4
Chlorpyrifos-Methyl SCHEMBL27546 0.78 TDP1 (1.00) TDP1MEN1KMT2AALDH1A1CYP3A4
Chlorpyrifos-Methyl SCHEMBL21647865 0.78 TDP1 (1.00) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL990015 0.78 TDP1 (0.51) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL11416872 0.77 TDP1 (0.67) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL27318027 0.76 TDP1 (0.53) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL11317244 0.75 TDP1 (0.65) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL11312487 0.75 TDP1 (0.65) TDP1MEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
CN-101209047-A Synergistic compositions SYNGENTA PARTICIPATIONS AG (CH) 2008-07-02 CN claimed
CN-1868278-A Synergistic compositions SYNGENTA PARTICIPATIONS AG (CH) 2006-11-29 CN claimed
US-20050132500-A1 Composition for impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2005-06-23 US claimed
CN-1554233-A Synergistic composition �����ɷ� 2004-12-15 CN claimed
EP-0851008-B1 Paints inhibiting the chitin synthesis in arthropods, for the control of pests and allergens MATEO HERRERO MARIA PILAR (ES) 2004-05-06 EP claimed
CN-1099235-C Insecticidal and miticidal compositions AMERICAN CYANAMID CO (US) 2003-01-22 CN claimed
US-6200961-B1 FREE OF VOLATILE ORGANIC COMPOUNDS, STABILITY; FOR CONTROLLING INSECTS AQUATROLS CORPORATION OF AMERICA, INC. 2001-03-13 US claimed
EP-1043927-A1 AGROCHEMICAL EMULSIFIABLE CONCENTRATES Aquatrols Holding Co., Inc. (US) 2000-10-18 EP claimed
EP-0017339-B1 INSECTICIDAL SYNERGISTIC COMPOSITION CONTAINING O,O-DIETHYL O-(3,5,6-TRICHLORO-2-PYRIDINYL)PHOSPHOROTHIOATE AND O-ETHYL O-(2-CHLORO-4-BROMOPHENYL)-S-N-PROPYL PHOSPHOROTHIOATE AND METHOD OF CONTROLLING INSECTS THEREWITH THE DOW CHEMICAL COMPANY (US) 1982-11-24 EP claimed
US-4301154-A FOR CONTROLLING MOTHS THE DOW CHEMICAL COMPANY (US) 1981-11-17 US claimed
US-4301155-A Insecticidal synergistic mixtures of O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and 2,2,3,3-tetramethylcyclopropanecarboxylic acid:cyano(3-phenoxyphenyl)methyl ester THE DOW CHEMICAL COMPANY (US) 1981-11-17 US claimed
US-4301156-A FOR MOTHS THE DOW CHEMICAL COMPANY (US) 1981-11-17 US claimed
EP-0028073-A1 Insecticidal synergistic mixtures of 0,0-diethyl 0-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and (+/-)-alpha-cyano 3-phenoxybenzyl-(+/-)-cis-trans-2,2-dimethyl-3-(2,2-dichlorovinyl) cyclopropane carboxylate and method of killing and controlling insects THE DOW CHEMICAL COMPANY (US) 1981-05-06 EP claimed
EP-0027326-A1 Insecticidal synergistic mixtures of 0,0-diethyl 0-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and 2,2,3,3-tetramethylcyclopropane-carboxylic acid: cyano(3-phenoxyphenyl) methyl ester and method of killing and controlling insects THE DOW CHEMICAL COMPANY (US) 1981-04-22 EP claimed
EP-0026650-A2 Insecticidal synergistic mixtures of 0,0-diethyl 0-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and 4-chloro-alpha-(1-methylethyl)benzene-acetic acid:cyano(6-phenoxy-2-pyridinyl)methyl ester and method of killing and controlling insects THE DOW CHEMICAL COMPANY (US) 1981-04-08 EP claimed
EP-0017339-A1 Insecticidal synergistic composition containing O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O-ethyl O-(2-chloro-4-bromophenyl)-S-n-propyl phosphorothioate and method of controlling insects therewith THE DOW CHEMICAL COMPANY (US) 1980-10-15 EP claimed
US-4223026-A Insecticidal synergistic mixture of O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O-ethyl O-(2-chloro-4-bromophenyl)-S-n-propyl phosphorothioate THE DOW CHEMICAL COMPANY (US) 1980-09-16 US claimed
US-4213975-A Insecticidal synergistic mixtures of O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O-ethyl O-(4-(methylthio)phenyl)-S-n-propyl phosphorothioate THE DOW CHEMICAL COMPANY (US) 1980-07-22 US claimed