Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16506502 | 0.85 | TDP1 (0.54) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11430337 | 0.83 | TDP1 (0.35) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL634976 | 0.78 | TDP1 (0.64) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL117867 | 0.75 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL6736860 | 0.75 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL30538657 | 0.75 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL23909395 | 0.73 | TDP1 (0.40) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3638775 | 0.71 | TDP1 (0.47) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorphrifos Oxon SCHEMBL30674408 | 0.71 | TDP1 (0.68) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorphrifos Oxon SCHEMBL1168184 | 0.71 | TDP1 (0.68) | TDP1MEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050132500-A1 | Composition for impregnation of fibers, fabrics and nettings imparting a protective activity against pests | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | US | claimed |
| US-5616253-A | Dechlorination of TCE with palladized iron | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-04-01 | — | — | US | claimed |
| US-5611936-A | Dechlorination of TCE with palladized iron | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-03-18 | — | — | US | claimed |
| US-4777164-A | PYRIDYL PHOSPHORAMIDATES OR PHOSPHORAMIDOTHIDATES | THE DOW CHEMICAL COMPANY (US) | 1988-10-11 | — | — | US | claimed |
| EP-0185778-A1 | Method and composition for enhancing the insecticidal activity of certain organophosphorus compounds | THE DOW CHEMICAL COMPANY (US) | 1986-07-02 | — | — | EP | claimed |
| EP-0065851-B1 | INSECTICIDAL SYNERGISTIC MIXTURES OF O,O-DIETHYL O-(3,5,6-TRICHLORO-2-PYRIDINYL)PHOSPHOROTHIOATE AND O,O-DIMETHYL-S-(N-METHYLCARBAMOYLMETHYL)PHOSPHOROTHIOATE AND METHOD OF KILLING AND CONTROLLING INSECTS | THE DOW CHEMICAL COMPANY (US) | 1986-06-25 | — | — | EP | claimed |
| US-4489068-A | Method and composition for enhancing the insecticidal activity of certain organophosphorus compounds | THE DOW CHEMICAL COMPANY (US) | 1984-12-18 | — | — | US | claimed |
| EP-0027011-B1 | INSECTICIDAL SYNERGISTIC MIXTURES OF 0,0-DIETHYL 0-(3,5,6-TRICHLORO-2-PYRIDINYL) PHOSPHOROTHIOATE AND 3-(2,2-DICHLOROETHENYL)-2,2-DIMETHYL-CYCLOPROPANE CARBOXYLIC ACID: CYANO (6-PHENOXY-2-PYRIDINYL) METHYL ESTER AND METHOD OF KILLING AND CONTROLLING INSECTS | THE DOW CHEMICAL COMPANY (US) | 1983-06-29 | — | — | EP | claimed |
| US-4380537-A | ORGANO PHOSPHORUS COMPOUND AND A LACTONE | THE DOW CHEMICAL COMPANY (US) | 1983-04-19 | — | — | US | claimed |
| US-4362722-A | MITICIDE FOR CATTLE | ICI AUSTRALIA LIMITED (AU) | 1982-12-07 | — | — | US | claimed |
| EP-0065851-A1 | Insecticidal synergistic mixtures of O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O,O-dimethyl-S-(N-methylcarbamoylmethyl)phosphorothioate and method of killing and controlling insects | THE DOW CHEMICAL COMPANY (US) | 1982-12-01 | — | — | EP | claimed |
| EP-0017339-B1 | INSECTICIDAL SYNERGISTIC COMPOSITION CONTAINING O,O-DIETHYL O-(3,5,6-TRICHLORO-2-PYRIDINYL)PHOSPHOROTHIOATE AND O-ETHYL O-(2-CHLORO-4-BROMOPHENYL)-S-N-PROPYL PHOSPHOROTHIOATE AND METHOD OF CONTROLLING INSECTS THEREWITH | THE DOW CHEMICAL COMPANY (US) | 1982-11-24 | — | — | EP | claimed |
| US-4301154-A | FOR CONTROLLING MOTHS | THE DOW CHEMICAL COMPANY (US) | 1981-11-17 | — | — | US | claimed |
| US-4301155-A | Insecticidal synergistic mixtures of O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and 2,2,3,3-tetramethylcyclopropanecarboxylic acid:cyano(3-phenoxyphenyl)methyl ester | THE DOW CHEMICAL COMPANY (US) | 1981-11-17 | — | — | US | claimed |
| US-4301156-A | FOR MOTHS | THE DOW CHEMICAL COMPANY (US) | 1981-11-17 | — | — | US | claimed |
| EP-0028073-A1 | Insecticidal synergistic mixtures of 0,0-diethyl 0-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and (+/-)-alpha-cyano 3-phenoxybenzyl-(+/-)-cis-trans-2,2-dimethyl-3-(2,2-dichlorovinyl) cyclopropane carboxylate and method of killing and controlling insects | THE DOW CHEMICAL COMPANY (US) | 1981-05-06 | — | — | EP | claimed |
| EP-0027326-A1 | Insecticidal synergistic mixtures of 0,0-diethyl 0-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and 2,2,3,3-tetramethylcyclopropane-carboxylic acid: cyano(3-phenoxyphenyl) methyl ester and method of killing and controlling insects | THE DOW CHEMICAL COMPANY (US) | 1981-04-22 | — | — | EP | claimed |
| EP-0017339-A1 | Insecticidal synergistic composition containing O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O-ethyl O-(2-chloro-4-bromophenyl)-S-n-propyl phosphorothioate and method of controlling insects therewith | THE DOW CHEMICAL COMPANY (US) | 1980-10-15 | — | — | EP | claimed |
| US-4223026-A | Insecticidal synergistic mixture of O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O-ethyl O-(2-chloro-4-bromophenyl)-S-n-propyl phosphorothioate | THE DOW CHEMICAL COMPANY (US) | 1980-09-16 | — | — | US | claimed |
| US-4213975-A | Insecticidal synergistic mixtures of O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and O-ethyl O-(4-(methylthio)phenyl)-S-n-propyl phosphorothioate | THE DOW CHEMICAL COMPANY (US) | 1980-07-22 | — | — | US | claimed |