Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL6350373 | 0.96 | CA2 (0.33) | CA2SLC34A1 | |
| Phosphoric Acid SCHEMBL10591141 | 0.91 | — | — | |
| Phosphoric Acid SCHEMBL27505743 | 0.91 | — | — | |
| Phosphoric Acid SCHEMBL5787354 | 0.91 | — | — | |
| Phosphoric Acid SCHEMBL5789293 | 0.87 | CA2 (0.33) | CA2SLC34A1 | |
| Phosphoric Acid SCHEMBL5805667 | 0.87 | CA2 (0.33) | CA2SLC34A1 | |
| Phosphoric Acid SCHEMBL5804227 | 0.86 | — | — | |
| Phosphoric Acid SCHEMBL5787357 | 0.86 | — | — | |
| Phosphoric Acid SCHEMBL5802753 | 0.86 | CA2 (0.39) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL404385 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6957743-B2 | Fluid water is passed through a purification material composed of apatite and absorption media in a fixed binder matrix. | WATERVISIONS INTERNATIONAL, INC. (US) | 2005-10-25 | — | — | US | disclosed |
| US-20030173287-A1 | Filter devices and methods of use | JOHNSTON ARTHUR W (US) | 2003-09-18 | — | — | US | disclosed |
| US-20030015467-A1 | Microbiological water filter | JOHNSTON ARTHUR W (US) | 2003-01-23 | — | — | US | disclosed |
| WO-2001087777-A2 | FILTER DEVICES AND METHODS OF USE | WATERVISIONS INTERNATIONAL, INC. (US) | 2001-11-22 | — | — | WO | disclosed |
| US-6187192-B1 | WATER CONTAINING BACTERIA AND/OR VIRUSES IS PASSED THROUGH A PURIFICATION MATERIAL COMPOSED OF APATITE AND ABSORPTION MEDIA IN A FIXED BINDER MATRIX | WATERVISIONS INTERNATIONAL, INC. | 2001-02-13 | — | — | US | disclosed |
| US-6180016-B1 | MIXTURE OF APATITE IN BINDER | WATERVISIONS INTERNATIONAL, INC. | 2001-01-30 | — | — | US | disclosed |