Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458716 | 0.96 | ALDH1A1 (0.45) | ALDH3A1ALDH1A3ALDH1A1PTGDR2ERN1 | |
| SCHEMBL7541512 | 0.95 | PTGDR2 (0.42) | ALDH3A1ALDH1A3ALDH1A1PTGDR2ERN1 | |
| SCHEMBL7543270 | 0.86 | ALDH1A1 (0.45) | ALDH3A1ALDH1A3ALDH1A1PTGDR2ERN1 | |
| SCHEMBL6517350 | 0.85 | PTGDR2 (0.40) | ALDH3A1ALDH1A3ALDH1A1PTGDR2ERN1 | |
| SCHEMBL7541400 | 0.84 | PTGDR2 (0.46) | ALDH1A1PTGDR2ERN1KMT2AMEN1 | |
| SCHEMBL7544691 | 0.84 | PTGDR2 (0.41) | ALDH1A1PTGDR2ERN1KMT2AMEN1 | |
| SCHEMBL7487895 | 0.84 | ALDH3A1 (0.41) | ALDH3A1ALDH1A3ALDH1A1PTGDR2ERN1 | |
| SCHEMBL3458964 | 0.83 | ALDH3A1 (0.42) | ALDH3A1ALDH1A3ALDH1A1PTGDR2ERN1 | |
| SCHEMBL7684624 | 0.83 | PTGDR2 (0.45) | ALDH1A1PTGDR2ERN1KMT2AMEN1 | |
| SCHEMBL3157614 | 0.82 | PTGDR2 (0.40) | ALDH1A3ALDH1A1PTGDR2ERN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1211239-A1 | PROCESS FOR THE PREPARATION OF 2,3-DIHYDROAZEPINE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2002-06-05 | — | — | EP | disclosed |