SCHEMBL6350818

SCHEMBL6350818

O=C(O)c1ccc(-c2c3ccccc3c(-c3ccc(C(=O)O)cc3)c3ccccc23)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.59
TSHR P16473 2/20 0.56
DAO P14920 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
TP53 P04637 1/20 0.55
SRD5A2 P31213 3/20 0.54
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
MAP2K4 P45985 1/20 0.53
EGFR P00533 1/20 0.52
BCL2L1 Q07817 1/20 0.50
BAD Q92934 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
TNKS O95271 1/20 0.49
EPHX2 P34913 1/20 0.49
NR1H4 Q96RI1 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29388499 1.00 TTR (0.59) TTRTSHRDAONAPRTTP53
SCHEMBL24222067 0.89 TTR (0.49) TTRTSHRDAONAPRTTP53
SCHEMBL30079577 0.89 TTR (0.49) TTRTSHRDAONAPRTTP53
SCHEMBL18687042 0.88 EGFR (0.65) TTRTSHRDAONAPRTSRD5A2
SCHEMBL28318765 0.87 ALDH1A1 (0.66) TTRTSHRDAONAPRTTP53
SCHEMBL21164720 0.86 KDM4E (0.55) TTRTSHRDAONAPRTTP53
SCHEMBL28601450 0.86 ATM (0.57) TTRTSHRDAONAPRTMAP2K4
SCHEMBL11593128 0.86 TTR (0.63) TTRTSHRDAONAPRTTP53
SCHEMBL31492950 0.86 TTR (0.63) TTRTSHRDAONAPRTTP53
SCHEMBL31492949 0.86 TTR (0.63) TTRTSHRDAONAPRTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4338175-B1 FAST AND LOW RE -ABSORPTION COMPOSITE SCINTILLATOR AND PROCESS FOR DETECTING HIGH-ENERGY PARTICLES AND/OR ELECTROMAGNETIC RADIATION UNIV DEGLI STUDI DI MILANO BICOCCA (IT) 2025-03-26 EP claimed
EP-4338175-A1 FAST AND LOW RE -ABSORPTION COMPOSITE SCINTILLATOR AND PROCESS FOR DETECTING HIGH-ENERGY PARTICLES AND/OR ELECTROMAGNETIC RADIATION Università Degli Studi Di Milano - Bicocca (IT) 2024-03-20 EP claimed
WO-2023201870-A1 CRYSTAL, METHOD FOR PREPARING SAME, AND USE THEREOF AS BLUE FLUORESCENT SCINTILLATION MATERIAL 中国科学院福建物质结构研究所 2023-10-26 WO claimed
CN-115894951-B Sm-MOF preparation method and application of Sm-MOF in fluorescence identification and photocatalysis 聊城大学 2023-09-01 CN claimed
CN-115894951-A Preparation method of Sm-MOF and application of Sm-MOF in fluorescent recognition and photocatalysis 聊城大学 2023-04-04 CN claimed
CN-113651514-B Substrate modifier for submerged ecological restoration and preparation method thereof 广州和源生态科技发展股份有限公司 2023-03-21 CN claimed
WO-2022238928-A1 FAST AND LOW RE -ABSORPTION COMPOSITE SCINTILLATOR AND PROCESS FOR DETECTING HIGH-ENERGY PARTICLES AND/OR ELECTROMAGNETIC RADIATION UNIVERSITA' DEGLI STUDI DI MILANO - BICOCCA (IT) 2022-11-17 WO claimed
US-11454581-B2 Molecule detecting apparatus KABUSHIKI KAISHA TOSHIBA (JP) 2022-09-27 US claimed
CN-114045138-A Frame sealing glue, display panel and preparation method thereof TCL华星光电技术有限公司 2022-02-15 CN claimed
CN-113651514-A Substrate modifier for submerged ecological restoration and preparation method thereof 广州和源生态科技发展股份有限公司 2021-11-16 CN claimed
US-20200256778-A1 MOLECULE DETECTING APPARATUS KABUSHIKI KAISHA TOSHIBA (JP) 2020-08-13 US claimed
CN-106010510-B A kind of multifunctional rare-earth metal-organic framework material converted for light and preparation method thereof 武汉大学 2018-07-03 CN claimed
CN-106010510-A Multifunctional rare-earth metal organic framework material used for light conversion and preparation method thereof 武汉大学 2016-10-12 CN claimed
US-12638602-B2 Metal organic framework particles as radioisotope detectors ARIZONA BOARD OF REGENTS OF BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-05-26 US disclosed
US-20240424488-A1 High-Entropy Metal-Organic Frameworks NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2024-12-26 US disclosed
US-20240280712-A1 METAL ORGANIC FRAMEWORK PARTICLES AS RADIOISOTOPE DETECTORS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2024-08-22 US disclosed
CN-106010510-B A kind of multifunctional rare-earth metal-organic framework material converted for light and preparation method thereof 武汉大学 2018-07-03 CN disclosed
CN-106010510-A Multifunctional rare-earth metal organic framework material used for light conversion and preparation method thereof 武汉大学 2016-10-12 CN disclosed
WO-2015068858-A1 SOLVENT-FREE PHOTON UPCONVERSION SYSTEM KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-05-14 WO disclosed
US-20050203269-A1 Dicarboxylic acids for dielectrics having barrier effect against copper diffusion INFINEON TECHNOLOGIES AG (DE) 2005-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638602-B2 Metal organic framework particles as radioisotope detectors SLCO1A2, SLCO4C1, SLCO2A1 TTR 1529/4885TSHR 934/4885DAO 4497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.