SCHEMBL6351058

SCHEMBL6351058

CCCCc1cc(O)c(O)c(O)c1

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.72
HPGD P15428 1/20 0.72
MAPK1 P28482 1/20 0.72
HTT P42858 1/20 0.72
RAB9A P51151 1/20 0.72
NPSR1 Q6W5P4 1/20 0.72
PTGS2 P35354 4/20 0.56
CYP3A4 P08684 1/20 0.56
TYR P14679 1/20 0.45
TRPV1 Q8NER1 1/20 0.45
PPARA Q07869 1/20 0.44
ESR1 P03372 1/20 0.44
GPR84 Q9NQS5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6356508 0.93 PTGS2 (0.65) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL28797776 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL5790509 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL5789723 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL5790435 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL28797794 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL5788838 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL28946092 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL5788482 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL13765878 0.91 PTGS2 (0.67) NPC1HPGDMAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4954659-A FOOD PRESERVATIVE CHEMEX PHARMACEUTICALS, INC. (US) 1990-09-04 US claimed
US-4181545-A POT LIFE OF HYDROXY POLYBUTADIENE UNITED TECHNOLOGIES CORPORATION (US) 1980-01-01 US claimed
EP-3571180-B1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF UNIV LEUVEN KATH (BE) 2024-12-18 EP disclosed
US-20210070684-A1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2021-03-11 US disclosed
CN-110312698-A Between producing high-purity, bis- (4- alkylphenol) derivatives of m- coupling and application thereof 鲁汶天主教大学 2019-10-08 CN disclosed
US-20180273722-A1 RESIN COMPOSITION ZEON CORPORATION (JP) 2018-09-27 US disclosed
EP-3345971-A1 RESIN COMPOSITION Zeon Corporation (JP) 2018-07-11 EP disclosed
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US disclosed
CN-1153798-C Process for producing polycarbonate 出光石油化学株式会社 2004-06-16 CN disclosed
US-20040072681-A1 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2004-04-15 US disclosed
EP-1260524-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Titanium Co., Ltd. (JP) 2002-11-27 EP disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
US-4418037-A PYROGALLOL DERIVATIVE STORAGE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 1983-11-29 US disclosed
US-4181545-A POT LIFE OF HYDROXY POLYBUTADIENE UNITED TECHNOLOGIES CORPORATION (US) 1980-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210070684-A1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF MMS19, PCBP1, PBRM1 NPC1 3662/4885HPGD 2431/4885MAPK1 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.