Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 4/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GNA15 | P30679 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193750 | 0.85 | CYP3A4 (0.60) | CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL6358411 | 0.84 | CYP3A4 (0.49) | CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL23409099 | 0.76 | GRM2 (0.49) | CYP2C9CYP1A2CYP2C19GRM2HDAC8 | |
| SCHEMBL6351492 | 0.74 | CYP3A4 (0.81) | CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6360654 | 0.74 | CYP3A4 (0.50) | CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6360618 | 0.73 | CYP3A4 (0.61) | CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6 | |
| Bromide SCHEMBL11794209 | 0.73 | GRM2 (0.51) | GRM2HDAC8KDM4EALDH1A1HTT | |
| SCHEMBL10532145 | 0.73 | ATP4A (0.61) | CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6350755 | 0.73 | CYP3A4 (0.67) | CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6417257 | 0.72 | CYP3A4 (0.66) | CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154007-A1 | New compounds | AMIN KOSRAT (SE) | 2005-07-14 | — | — | US | disclosed |
| US-6790960-B2 | Compounds | ASTRAZENECA AB (SE) | 2004-09-14 | — | — | US | disclosed |
| EP-1411056-A2 | Imidazo[1,2-a]pyridine compounds that inhibit gastric acid secretion, pharmaceutical compositions thereof, and processes for their preparation | AstraZeneca AB (SE) | 2004-04-21 | — | — | EP | disclosed |
| US-20030220364-A1 | New compounds | AMIN KOSRAT (SE) | 2003-11-27 | — | — | US | disclosed |
| US-6579884-B1 | Compounds | ASTRAZENECA AB (SE) | 2003-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220364-A1 | New compounds | SLC10A2, GIPR, FABP2 | CYP2C9 3074/4885CYP3A4 2404/4885CYP1A2 1919/4885 |
| US-20050154007-A1 | New compounds | SLC10A2, GIPR, FABP6 | CYP2C9 3139/4885CYP3A4 2475/4885CYP1A2 2011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.