Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | CTSA | P10619 | 5/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGAV | P06756 | 3/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859119 | 0.86 | SMN1; SMN2 (0.53) | PRNPNPSR1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6355786 | 0.85 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAHTTNCOA1 | |
| SCHEMBL4630107 | 0.81 | PRNP (0.51) | PRNPNPSR1RXFP1CTSAITGB3 | |
| SCHEMBL4630103 | 0.81 | PRNP (0.51) | PRNPNPSR1RXFP1CTSAITGB3 | |
| SCHEMBL10680501 | 0.78 | SLC6A9 (0.51) | ALDH1A1SMN1; SMN2LMNAHTTNCOA1 | |
| SCHEMBL4867418 | 0.78 | CNR2 (0.45) | ALDH1A1SMN1; SMN2LMNAHTTNCOA1 | |
| SCHEMBL21274965 | 0.77 | PRNP (0.60) | PRNPNPSR1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16681340 | 0.76 | CTSA (0.45) | PRNPNPSR1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16681339 | 0.76 | CTSA (0.45) | PRNPNPSR1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4862572 | 0.76 | HTT (0.69) | ALDH1A1SMN1; SMN2LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1643158-A | Process for preparing optically active beta-aminocarboxylic acids from racemic N-acylated beta-aminocarboxylic acids | DEGUSSA (DE) | 2005-07-20 | — | — | CN | disclosed |
| US-20050153401-A1 | Process for preparing optically active beta-aminocarboxylic acids from racemic n-acylated beta-aminocarboxylic acids | DEGUSSA AG (DE) | 2005-07-14 | — | — | US | disclosed |
| EP-1487990-A2 | PROCESS FOR PREPARING OPTICALLY ACTIVE BETA-AMINOCARBOXYLIC ACIDS FROM RACEMIC N-ACYLATED BETA-AMINOCARBOXYLIC ACIDS | Degussa AG (DE) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080854-A2 | PROCESS FOR PREPARING OPTICALLY ACTIVE BETA-AMINOCARBOXYLIC ACIDS FROM RACEMIC N-ACYLATED BETA-AMINOCARBOXYLIC ACIDS | DEGUSSA AG (DE) | 2003-10-02 | — | — | WO | disclosed |