Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357550 | 0.86 | ACHE (0.45) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL11422554 | 0.83 | ACHE (0.47) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL11333088 | 0.80 | ACHE (0.44) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL29133209 | 0.78 | ACHE (0.50) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL1913740 | 0.78 | ACHE (0.50) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL29133227 | 0.78 | ACHE (0.50) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL29133238 | 0.78 | ACHE (0.50) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL11343859 | 0.78 | ACHE (0.50) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL8507982 | 0.78 | ACHE (0.50) | ACHENPSR1MEN1KMT2ALMNA | |
| SCHEMBL29133236 | 0.78 | ACHE (0.50) | ACHENPSR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234257-A1 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | LOYOLA UNIVERSITY OF CHICAGO | 2005-10-20 | — | — | US | disclosed |
| US-6909010-B2 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | LOYOLA UNIVERSITY OF CHICAGO (US) | 2005-06-21 | — | — | US | disclosed |
| US-20030060648-A1 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | LOYOLA UNIVERSITY OF CHICAGO | 2003-03-27 | — | — | US | disclosed |
| WO-2002085918-A1 | A FACILE SYNTHESIS OF SYMMETRIC ESTERS OF ALKYLENEBISPHOSPHONIC ACIDS | LOYOLA UNIVERSITY OF CHICAGO (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060648-A1 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | PHOSPHO1, ADH1C, PAICS | ACHE 2155/4885NPSR1 2048/4885MEN1 286/4885 |
| US-20050234257-A1 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | PHOSPHO1, PAPSS1, PHPT1 | ACHE 1481/4885NPSR1 1387/4885MEN1 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.