Tetrahydrofuran

Tetrahydrofuran

SCHEMBL635322

C1CCOC1.CC(C)O.CC(N)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
LMNA P02545 1/20 0.35
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL154168 0.91
Tetrahydrofuran SCHEMBL2143001 0.88 ALDH1A1 (0.53) ALDH1A1LMNAPKMSMN1; SMN2
Isopropyl Alcohol SCHEMBL9004332 0.88 ALDH1A1 (0.53) ALDH1A1LMNAPKMSMN1; SMN2
Tetrahydrofuran SCHEMBL16738662 0.88 ALDH1A1 (0.53) ALDH1A1LMNAPKMSMN1; SMN2
Tetrahydrofuran SCHEMBL28780075 0.84
Tetrahydrofuran SCHEMBL10386650 0.80 ALDH1A1 (0.44) ALDH1A1LMNAPKMSMN1; SMN2
Tetrahydrofuran SCHEMBL28299228 0.80 ALDH1A1 (0.44) ALDH1A1LMNAPKMSMN1; SMN2
Tetrahydrofuran SCHEMBL27823038 0.79 ALDH1A1 (0.50) ALDH1A1PKMSMN1; SMN2
Tetrahydrofuran SCHEMBL23455755 0.78 ALDH1A1 (0.42) ALDH1A1LMNA
Tetrahydrofuran SCHEMBL9765640 0.78 ALDH1A1 (0.42) ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2961521-A1 ASYMMETRICALLY POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER Wacker Chemie AG (DE) 2016-01-06 EP disclosed
WO-2015003880-A1 ASYMMETRICALLY POROUS MEMBRANES MADE OF ALDEHYDE-CROSSLINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2015-01-15 WO disclosed
WO-2014131673-A1 ASYMMETRICALLY POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2014-09-04 WO disclosed
EP-2315626-B1 POROUS MEMBRANES MADE UP OF ORGANOPOLYSILOXANE COPOLYMERS WACKER CHEMIE AG (DE) 2012-02-22 EP disclosed