Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL23711833 | 0.81 | TSHR (0.56) | ALDH1A1TSHRTDP1USP2SMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL4133541 | 0.81 | TDP1 (0.56) | ALDH1A1TSHRTDP1USP2SMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL28093479 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHR | |
| Tetrahydrofuran SCHEMBL154168 | 0.80 | — | — | |
| Fluoride SCHEMBL29094701 | 0.80 | — | — | |
| Fluoride SCHEMBL1055336 | 0.80 | — | — | |
| Tetrahydrofuran SCHEMBL10660627 | 0.79 | TDP1 (0.53) | ALDH1A1TSHRTDP1USP2KDM4E | |
| Tetrahydrofuran SCHEMBL635322 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL2143001 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHRUSP2LMNASMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL16738662 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHRUSP2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063075-A | Amide ether derivatives as low calorie fat mimetics | NABISCO BRANDS, INC. (US) | 1991-11-05 | — | — | US | disclosed |