3-Hydroxybutyric Acid, (+/-)-

3-Hydroxybutyric Acid, (+/-)-

SCHEMBL6353320

CC(O)CC(=O)O.c1cc2cc(c1)O2

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.37
CYP1A2 P05177 1/20 0.36
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
FOLH1 Q04609 1/20 0.35
CTSA P10619 1/20 0.35
POLB P06746 1/20 0.35
CPA1 P15085 2/20 0.34
GABBR2 O75899 1/20 0.34
GABBR1 Q9UBS5 1/20 0.34
CPB1 P15086 1/20 0.34
CPA3 P15088 1/20 0.34
CPB2 Q96IY4 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL11833224 0.78 FFAR3 (0.46) SMN1; SMN2POLB
Biphenyl SCHEMBL5907627 0.76 MMP12 (0.53) FFAR1CYP1A2HTT
(R)-3-Hydroxybutanoate SCHEMBL60959 0.74
(R)-3-Hydroxybutanoate SCHEMBL1533862 0.74 SLC22A6 (0.56) SMN1; SMN2SLC22A6
3-Hydroxybutyric Acid, (+/-)- SCHEMBL28197574 0.74 SLC22A6 (0.56) SMN1; SMN2SLC22A6
(R)-3-Hydroxybutanoate SCHEMBL336331 0.74
3-Hydroxybutyric Acid, (+/-)- SCHEMBL1881926 0.74 SLC22A6 (0.56) SMN1; SMN2SLC22A6
(R)-3-Hydroxybutanoate SCHEMBL29903959 0.74
3-Hydroxybutyric Acid, (+/-)- SCHEMBL1897117 0.74 SLC22A6 (0.56) SMN1; SMN2SLC22A6
3-Hydroxybutyric Acid, (+/-)- SCHEMBL2731 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6861550-B2 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2005-03-01 US disclosed
US-20030100084-A1 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2003-05-29 US disclosed
EP-1130042-A2 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2001-09-05 EP disclosed