SCHEMBL6353365

SCHEMBL6353365

O=C(Cl)c1ccc(Oc2ccc(C(c3ccccc3)(c3ccccc3)c3ccc(Oc4ccc(C(=O)Cl)cc4)cc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.49
SRD5A2 P31213 4/20 0.47
HPGD P15428 2/20 0.45
PGR P06401 1/20 0.44
MAPK14 Q16539 2/20 0.43
KCNQ3 O43525 1/20 0.43
KCNQ2 O43526 1/20 0.43
KCNE1 P15382 1/20 0.43
KCNQ1 P51787 1/20 0.43
MAPT P10636 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ERCC5 P28715 1/20 0.42
FEN1 P39748 1/20 0.42
MMP1 P03956 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5718787 0.98 PARP10 (0.47) PARP10SRD5A2HPGDPGRMAPK14
SCHEMBL6351953 0.86 SRD5A2 (0.65) PARP10SRD5A2HPGDTSHRPARP15
SCHEMBL9249310 0.85 PARP10 (0.64) PARP10SRD5A2HPGDPGRKCNQ3
SCHEMBL21786 0.85 PARP10 (0.64) PARP10SRD5A2HPGDPGRKCNQ3
Diphenylether SCHEMBL9717017 0.83 PARP10 (0.61) PARP10SRD5A2PGRKCNQ3KCNQ2
SCHEMBL14265410 0.82 SRD5A2 (0.56) SRD5A2HPGDMAPTL3MBTL1HTT
Hydrochloric Acid SCHEMBL10411245 0.82 PARP10 (0.60) PARP10SRD5A2PGRKCNQ3KCNQ2
SCHEMBL272345 0.81 PARP10 (0.58) PARP10SRD5A2HPGDMAPTTSHR
SCHEMBL8715862 0.81 LTA4H (0.55) PARP10HPGDPGRMAPTTSHR
SCHEMBL9786679 0.81 PARP10 (0.58) PARP10SRD5A2HPGDMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050203269-A1 Dicarboxylic acids for dielectrics having barrier effect against copper diffusion INFINEON TECHNOLOGIES AG (DE) 2005-09-15 US disclosed