Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13198683 | 1.00 | KDM4E (0.38) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL25641876 | 1.00 | KDM4E (0.38) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL14827587 | 1.00 | KDM4E (0.38) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL30363373 | 0.87 | ALDH1A1 (0.44) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL147771 | 0.87 | ALDH1A1 (0.44) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL14827588 | 0.87 | ALDH1A1 (0.44) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL18461270 | 0.87 | ALDH1A1 (0.44) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7197213 | 0.87 | ALDH1A1 (0.44) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5732376 | 0.87 | ALDH1A1 (0.44) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28062749 | 0.87 | ALDH1A1 (0.44) | KDM4ECYP2C19ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714087-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20090137757-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | IMUTA JUNICHI | 2009-05-28 | — | — | US | disclosed |
| US-7393907-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-20050159614-A1 | Norbornane based cycloaliphatic compounds containing nitrile groups | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159614-A1 | Norbornane based cycloaliphatic compounds containing nitrile groups | NISCH, PAH, CYP1B1 | KDM4E 4004/4885CYP2C19 556/4885ALDH1A1 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.