Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363373 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL5732376 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL18461270 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL147771 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL14827588 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL28062749 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL31042709 | 0.94 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL1286040 | 0.92 | POLB (0.56) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL392898 | 0.92 | POLB (0.56) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL960068 | 0.92 | POLB (0.56) | ALDH1A1SMN1; SMN2POLBHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021670-A1 | PALLADIUM (II) CATALYZED POLYMERIZATION OF NORBORNENE AND ACRYLATES | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-03-29 | — | — | WO | claimed |
| US-6111041-A | CONTACTING ACRYLATE AND/OR NORBORNENE MONOMER REACTANT UNDER POLYMERIZATION CONDITIONS AND IN THE PRESENCE OF A SOLVENT WITH A CATALYST SYSTEM CONSISTING ESSENTIALLY OF A PD(II) DIMER COMPONENT | THE PENN STATE RESEARCH FOUNDATION (US) | 2000-08-29 | — | — | US | claimed |
| US-20130081999-A1 | Bridged Macrocyclic Module Compositions | WHITEFORD JEFFERY A (US) | 2013-04-04 | — | — | US | disclosed |
| US-6593440-B2 | Hardness and adhesive properties, high-temperature stability | PENN STATE RESEARCH FOUNDATION | 2003-07-15 | — | — | US | disclosed |
| US-20020040115-A1 | Palladium (II) catalyzed polymerization of norbornene and acrylates | PENN STATE RESEARCH FOUNDATION, THE | 2002-04-04 | — | — | US | disclosed |
| US-6300440-B1 | PALLADIUM DIMER CONTAINING NITROGEN OR PHOSPHORUS LIGAND | THE PENN STATE RESEARCH FOUNDATION | 2001-10-09 | — | — | US | disclosed |
| US-6111041-A | CONTACTING ACRYLATE AND/OR NORBORNENE MONOMER REACTANT UNDER POLYMERIZATION CONDITIONS AND IN THE PRESENCE OF A SOLVENT WITH A CATALYST SYSTEM CONSISTING ESSENTIALLY OF A PD(II) DIMER COMPONENT | THE PENN STATE RESEARCH FOUNDATION (US) | 2000-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130081999-A1 | Bridged Macrocyclic Module Compositions | SBDS, NCL, INTS6 | ALDH1A1 4017/4885SMN1; SMN2 3232/4885POLB 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.