Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226916 | 0.94 | TSHR (0.57) | TSHRCYP3A4MAPK1TDP1AHR | |
| SCHEMBL11548109 | 0.90 | TSHR (0.55) | TSHRCYP3A4MAPK1TDP1AHR | |
| SCHEMBL11685824 | 0.88 | TSHR (0.52) | TSHRCYP3A4MAPK1TDP1ALDH1A1 | |
| SCHEMBL11602077 | 0.80 | CYP3A4 (0.46) | TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL7555551 | 0.78 | TDP1 (0.44) | TSHRCYP3A4MAPK1TDP1ALDH1A1 | |
| SCHEMBL10493755 | 0.78 | CYP3A4 (0.44) | TSHRCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL10493709 | 0.78 | CYP3A4 (0.44) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL31092645 | 0.78 | TDP1 (0.44) | TSHRCYP3A4MAPK1TDP1ALDH1A1 | |
| SCHEMBL10969574 | 0.75 | CYP3A4 (0.41) | TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL10969576 | 0.75 | CYP3A4 (0.41) | TSHRCYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178121-A | Preparation method of 2,4, 5-trifluoro-benzaldehyde | 浙江巍华新材料股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| US-4191711-A | Process for the preparation of certain nuclear chlorinated benzotrichlorides | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | claimed |
| CN-116178121-A | Preparation method of 2,4, 5-trifluoro-benzaldehyde | 浙江巍华新材料股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116178121-A | Preparation method of 2,4, 5-trifluoro-benzaldehyde | 浙江巍华新材料股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| EP-1528052-B1 | Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel | FINCHIMICA SRL (IT) | 2013-07-31 | — | — | EP | disclosed |
| US-6949648-B2 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-27 | — | — | US | disclosed |
| EP-1528052-A1 | Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel | FINCHIMICA S.p.A. (IT) | 2005-05-04 | — | — | EP | disclosed |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1270572-A1 | CONDENSED PYRAZOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-4191711-A | Process for the preparation of certain nuclear chlorinated benzotrichlorides | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |
| US-4191711-A | Process for the preparation of certain nuclear chlorinated benzotrichlorides | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |
| US-4046656-A | Photochlorination process for methyl aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-3976769-A | INSECTICIDE | AIRWICK INDUSTRIES, INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | PTGS1, PTGIS, IL5 | TSHR 3782/4885CYP3A4 48/4885MAPK1 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.