Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555551 | 1.00 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL23591340 | 0.90 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL7057611 | 0.87 | TSHR (0.46) | TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL11684047 | 0.85 | TDP1 (0.39) | TDP1TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL8975014 | 0.85 | TDP1 (0.35) | TDP1TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL11548109 | 0.81 | TSHR (0.55) | TDP1TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL7272204 | 0.80 | NOTUM (0.42) | TDP1ALDH1A1 | |
| SCHEMBL6353876 | 0.78 | TSHR (0.52) | TDP1TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL13990527 | 0.78 | ALDH1A1 (0.34) | TDP1ALDH1A1KDM1AKDM1BMAPT | |
| SCHEMBL11226916 | 0.78 | TSHR (0.57) | TDP1TSHRCYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324627-A | Method for preparing 2, 4-dichloro-5-fluorobenzoyl chloride | 东南大学 | 2024-07-12 | — | — | CN | claimed |
| CN-118324627-A | Method for preparing 2, 4-dichloro-5-fluorobenzoyl chloride | 东南大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-118324627-A | Method for preparing 2, 4-dichloro-5-fluorobenzoyl chloride | 东南大学 | 2024-07-12 | — | — | CN | disclosed |