SCHEMBL6354069

SCHEMBL6354069

CC(C)(C)n1ccnc1S

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30
LPO P22079 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2930973 0.73 ALDH1A1 (0.38) TDP1LPO
SCHEMBL21341550 0.71 TDP1 (0.30) TDP1LPO
SCHEMBL21720018 0.71 ALDH1A1 (0.33) TDP1LPO
SCHEMBL21720267 0.71 MAPK13 (0.34) TDP1LPO
SCHEMBL422085 0.71 KCNH2 (0.33) TDP1LPO
SCHEMBL2625572 0.71 TLR8 (0.38) TDP1LPO
SCHEMBL16904743 0.71 ALDH1A1 (0.33) TDP1LPO
Hydrochloric Acid SCHEMBL21110936 0.70 KCNH2 (0.32)
SCHEMBL17946249 0.68 KMT2A (0.31) TDP1
SCHEMBL21720005 0.68 TNKS (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3709010-B1 METAL COMPLEX AS SENSOR COMPOUND FOR DETECTING GAS ANALYTE CARRIER CORP (US) 2025-04-23 EP disclosed
US-20200038378-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE GENENTECH, INC. 2020-02-06 US disclosed
US-6930076-B2 Nematicidal trifluorobutenyl imidazole thioether derivatives BAYER CROPSCIENCE AG (DE) 2005-08-16 US disclosed
US-20050080123-A1 Nematicidal trifluorobutenyl imidazole thioether derivatives BAYER CROPSCIENCE AG (DE) 2005-04-14 US disclosed
EP-1465490-A2 NEMATICIDAL TRIFLUOROBUTENYL IMIDAZOLE THIOETHER DERIVATIVES Bayer CropScience AG (DE) 2004-10-13 EP disclosed
WO-2003049541-A2 NEMATICIDAL TRIFLUOROBUTENYL IMIDAZOLE THIOETHER DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-06-19 WO disclosed
US-4973599-A ANTIINFLAMMATORY AGENTS HOFFMAN-LA ROCHE INC. (US) 1990-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080123-A1 Nematicidal trifluorobutenyl imidazole thioether derivatives TIAL1, MASTL, ATL3 TDP1 3640/4885LPO 3928/4885
US-20200038378-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ADRM1, BRAP, VHL TDP1 1259/4885LPO 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.