Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6354426 | 1.00 | CYP2C19 (0.61) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| SCHEMBL23901561 | 0.82 | CYP2C19 (0.64) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| SCHEMBL6234926 | 0.76 | CYP2C19 (0.67) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| SCHEMBL5317134 | 0.76 | CYP2C19 (0.60) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| SCHEMBL8804832 | 0.75 | CYP2C19 (0.62) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| SCHEMBL6355710 | 0.74 | CYP2C19 (0.56) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| SCHEMBL6355713 | 0.74 | CYP2C19 (0.56) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL5967107 | 0.74 | CYP2C19 (0.61) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| SCHEMBL2565526 | 0.74 | KMT2A (0.61) | CYP2C19CYP2D6CYP2C9RECQLKMT2A | |
| SCHEMBL30781045 | 0.74 | TSHR (0.61) | CYP2C19CYP2D6CYP2C9KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119481-A1 | Novel amidine derivatives and the use of the same in pharmaceuticals | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-02 | — | — | US | disclosed |
| EP-1453794-A1 | NOVEL AMIDINE DERIVATIVES AND THE USE OF THE SAME IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003053914-A1 | NOVEL AMIDINE DERIVATIVES AND THE USE OF THE SAME IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119481-A1 | Novel amidine derivatives and the use of the same in pharmaceuticals | NGLY1, OAT, SLC10A1 | CYP2C19 594/4885CYP2D6 466/4885CYP2C9 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.