Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17704773 | 0.86 | KMT2A (0.53) | POLBKMT2AKDM4EFAAHPHGDH | |
| SCHEMBL9456596 | 0.82 | KMT2A (0.50) | POLBKMT2AKDM4EFAAHPHGDH | |
| SCHEMBL61173 | 0.82 | POLB (0.55) | POLBKMT2AKDM4EFAAHPHGDH | |
| SCHEMBL31339223 | 0.80 | HTT (0.49) | POLBKMT2AKDM4EFAAHPHGDH | |
| SCHEMBL5794581 | 0.78 | KMT2A (0.47) | POLBKMT2AKDM4EFAAHPHGDH | |
| SCHEMBL6354517 | 0.77 | NPSR1 (0.58) | POLBKMT2AL3MBTL1HTTNPSR1 | |
| SCHEMBL194085 | 0.77 | HTT (0.46) | POLBKMT2AKDM4EFAAHPHGDH | |
| SCHEMBL320116 | 0.77 | POLB (0.59) | POLBKMT2AKDM4EFAAHPHGDH | |
| SCHEMBL455438 | 0.77 | KMT2A (0.53) | POLBKMT2AKDM4EFAAHPHGDH | |
| SCHEMBL24896437 | 0.75 | PLAU (0.51) | POLBKMT2AKDM4EFAAHPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979629-B | Oxime derivatives and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-112979628-B | Diphenyl ether substituted oxime derivative and its application in agriculture | 东莞市东阳光农药研发有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-112110911-B | 1,3, 4-Oxadiazole oxime derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-112979633-B | Novel oxime derivative, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-114685393-A | Novel oxime derivative, preparation method thereof and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114195763-A | Benzoyl oxy substituted oxime derivative and application thereof | 东莞市东阳光农药研发有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-112979633-A | Oxime derivatives, their preparation and use | 东莞市东阳光农药研发有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112979628-A | Oxime derivative substituted by diphenyl ether and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112979629-A | Oxime derivatives and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112110911-A | 1,3, 4-oxadiazole oxime derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-110914261-B | Oxadiazole oxime derivative and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-103087022-B | Oxalyl-substituted-3-aryltetronate compounds, and preparations and applications thereof | UNIV NANKAI | 2015-06-10 | — | — | CN | disclosed |
| US-7276511-B2 | Benzylamine derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-02 | — | — | US | disclosed |
| US-7276511-B2 | Benzylamine derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-02 | — | — | US | disclosed |
| US-7276511-B2 | Benzylamine derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-02 | — | — | US | disclosed |
| US-20060194841-A1 | E.g., N-{2-(3,4-dichlorophenyl)-2-[(3,3-diphenylpropionyl)-methylamino]-4-{spiro[benzo(c)thiophene-1(3H),4'-piperidine]-(2S)-oxide}-1'-yl-butyl}-3,3,3-trifluoro-N-methyl-propionamide hydrochloride, NK-1 or NK-2 receptor antagonists; irritable bowel syndrome, pain, anxiety, COPD, headaches and vomiting | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1650189-A1 | BENZYLAMINE DERIVATIVE | Zeria Pharmaceutical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194841-A1 | E.g., N-{2-(3,4-dichlorophenyl)-2-[(3,3-diphenylpropionyl)-methylamino]-4-{spiro[benzo(c)thiophene-1(3H),4'-piperidine]-(2S)-oxide}-1'-yl-butyl}-3,3,3-trifluoro-N-methyl-propionamide hydrochloride, NK-1 or NK-2 receptor antagonists; irritable bowel syndrome, pain, anxiety, COPD, headaches and vomiting | KCNAB1, BDKRB2, ARRB1 | POLB 1758/4885KMT2A 499/4885KDM4E 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.