SCHEMBL6354810

SCHEMBL6354810

CCNc1nc(Cl)nc(NCC(C)C)n1

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.73
ESR1 P03372 3/20 0.52
KMT2A Q03164 2/20 0.49
MAPT P10636 1/20 0.49
GAA P10253 3/20 0.48
TDP1 Q9NUW8 2/20 0.45
PDE4A P27815 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10168936 0.92 ESR1 (0.59) LMNAESR1KMT2AGAATDP1
SCHEMBL15094729 0.88 ESR1 (0.59) LMNAESR1KMT2AMAPTGAA
Simazine SCHEMBL9130727 0.85 LMNA (1.00) LMNAKMT2AMAPTGAATDP1
Simazine SCHEMBL8409822 0.85 LMNA (1.00) LMNAKMT2AMAPTGAATDP1
Simazine SCHEMBL37774 0.85 LMNA (1.00) LMNAKMT2AMAPTGAATDP1
Simazine SCHEMBL28076157 0.83 LMNA (0.95) LMNAKMT2AMAPTGAATDP1
SCHEMBL23431498 0.83 GAA (0.70) LMNAESR1KMT2AGAATDP1
Simazine SCHEMBL23716534 0.81 LMNA (0.91) LMNAKMT2AMAPTGAATDP1
Simazine SCHEMBL9123386 0.81 LMNA (0.91) LMNAKMT2AMAPTGAAPDE4A
Simazine SCHEMBL4731210 0.81 LMNA (0.91) LMNAKMT2AMAPTGAAPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050145565-A1 Method for preventing the uncontrolled growth of microorganisms BETA TEC HOPFENPRODUKTE GMBH (DE) 2005-07-07 US claimed
US-20020114856-A1 Compositions containing hops extract and their use in water systems and process streams to control biological fouling ONDEO NALCO COMPANY 2002-08-22 US claimed
US-6379720-B1 CONTROLLING ALGAE NALCO CHEMICAL COMPANY 2002-04-30 US claimed
WO-2002005637-A1 COMPOSITIONS CONTAINING HOPS EXTRACT AND THEIR USE IN WATER SYSTEMS AND PROCESS STREAMS TO CONTROL BIOLOGICAL FOULING ONDEO NALCO COMPANY (US) 2002-01-24 WO claimed
EP-1080641-A2 Composition and method for controlling biological growth using stabilized sodium hypobromite in synergistic combinations NALCO CHEMICAL COMPANY (US) 2001-03-07 EP claimed
WO-2001011954-A2 COMPOSITION AND METHOD FOR CONTROLLING BIOLOGICAL GROWTH USING STABILIZED SODIUM HYPOBROMITE IN SYNERGISTIC COMBINATIONS NALCO CHEMICAL COMPANY (US) 2001-02-22 WO claimed
US-20050145565-A1 Method for preventing the uncontrolled growth of microorganisms BETA TEC HOPFENPRODUKTE GMBH (DE) 2005-07-07 US disclosed
EP-0751170-B1 Silicone derivatives, their production and use CHIBA FLOUR MILLING (JP) 2003-01-22 EP disclosed
US-20020114856-A1 Compositions containing hops extract and their use in water systems and process streams to control biological fouling ONDEO NALCO COMPANY 2002-08-22 US disclosed
US-6379720-B1 CONTROLLING ALGAE NALCO CHEMICAL COMPANY 2002-04-30 US disclosed
WO-2002005637-A1 COMPOSITIONS CONTAINING HOPS EXTRACT AND THEIR USE IN WATER SYSTEMS AND PROCESS STREAMS TO CONTROL BIOLOGICAL FOULING ONDEO NALCO COMPANY (US) 2002-01-24 WO disclosed
CN-1069644-C Novel silicone derivatives,their production and use CHIBA FLOUR MILLING (JP) 2001-08-15 CN disclosed
US-5859243-A AMINOSILICONES HAVING PYRIMIDINYL GROUPS BOUND TO THE AMINO GROUPS; USED TO GEL SILICONE OIL OR TO INCREASE THE VISCOSITY STABLY AND HOMOGENEOUSLY; BASES FOR COSMETICS, DRUGS, INDUSTRIAL MATERIAL; FEEL; TEXTURE CHIBA FLOUR MILLING CO., LTD. (JP) 1999-01-12 US disclosed
US-5712391-A POLYSILOXANES MODIFIED WITH TRIAZINE GROUPS AND DIAMINE COMPOUNDS FOR COSMETICS CHIBA FLOUR MILLING CO., LTD. (JP) 1998-01-27 US disclosed
CN-1145907-A Novel silicone derivatives,their production and use CHIBA FLOUR MILLING (JP) 1997-03-26 CN disclosed
EP-0751170-A2 Silicone derivatives, their production and use Chiba Flour Milling Co., Ltd. (JP) 1997-01-02 EP disclosed
EP-0603240-A1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES MONSANTO COMPANY (US) 1994-06-29 EP disclosed
WO-1993003615-A1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES MONSANTO COMPANY (US) 1993-03-04 WO disclosed