Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Simazine SCHEMBL8409822 | 1.00 | LMNA (1.00) | LMNAKMT2AMAPTPDE4AGAA | |
| Simazine SCHEMBL37774 | 1.00 | LMNA (1.00) | LMNAKMT2AMAPTPDE4AGAA | |
| Simazine SCHEMBL28076157 | 0.97 | LMNA (0.95) | LMNAKMT2AMAPTPDE4AGAA | |
| Simazine SCHEMBL23716534 | 0.95 | LMNA (0.91) | LMNAKMT2AMAPTPDE4AGAA | |
| Simazine SCHEMBL9123386 | 0.95 | LMNA (0.91) | LMNAKMT2AMAPTPDE4AGAA | |
| Simazine SCHEMBL4731210 | 0.95 | LMNA (0.91) | LMNAKMT2AMAPTPDE4AGAA | |
| SCHEMBL4831154 | 0.95 | LMNA (0.90) | LMNAKMT2AMAPTPDE4AGAA | |
| SCHEMBL29609639 | 0.91 | LMNA (0.83) | LMNAKMT2AMAPTPDE4ACYP1A2 | |
| SCHEMBL7101507 | 0.91 | LMNA (0.83) | LMNAKMT2AMAPTPDE4ACYP1A2 | |
| SCHEMBL2356311 | 0.89 | LMNA (0.79) | LMNAKMT2AMAPTPDE4AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5460723-A | A water apparatus comprising at least one nanofiltration membrane mounted at the exit from the treatment to complete eliminating the microcontaminants | OMNIUM DE TRAITEMENT ET DE VALORRSATION (OTV) S.A. (FR) | 1995-10-24 | — | — | US | disclosed |