Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891536 | 0.81 | RXFP1 (0.41) | ALDH1A1HPGDHSD17B10PIK3R1PIK3CA | |
| SCHEMBL12920733 | 0.79 | GRM5 (0.39) | GRM5ALDH1A1HPGDHSD17B10PIK3R1 | |
| SCHEMBL6850328 | 0.77 | GRM5 (0.44) | GRM5ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL31286459 | 0.77 | PIK3R1 (0.32) | ALDH1A1HPGDHSD17B10PIK3R1PIK3CA | |
| SCHEMBL23571405 | 0.76 | GRM5 (0.37) | GRM5ALDH1A1PIK3R1PIK3CAKDM4E | |
| SCHEMBL24163731 | 0.76 | GRM5 (0.42) | GRM5ALDH1A1PIK3R1PIK3CAKDM4E | |
| SCHEMBL6217320 | 0.75 | GRM5 (0.43) | GRM5ALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL4654965 | 0.75 | RXFP1 (0.38) | GRM5ALDH1A1HPGDHSD17B10KDM4E | |
| Bromide SCHEMBL5306710 | 0.74 | RXFP1 (0.37) | GRM5ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL25096400 | 0.73 | KDM4E (0.38) | GRM5ALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154007-A1 | New compounds | AMIN KOSRAT (SE) | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154007-A1 | New compounds | SLC10A2, GIPR, FABP6 | GRM5 975/4885ALDH1A1 1838/4885HPGD 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.