Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.41 |
| ▸ | RXRB | P28702 | 4/20 | 0.41 |
| ▸ | RXRG | P48443 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | STS | P08842 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171804 | 0.85 | GAA (0.40) | NR5A2NR5A1 | |
| SCHEMBL5609738 | 0.84 | CNR2 (0.37) | PPARGPPARAS1PR2S1PR4S1PR1 | |
| SCHEMBL2695933 | 0.82 | ESR1 (0.44) | PPARAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL3347786 | 0.81 | GAA (0.43) | PPARGPPARA | |
| SCHEMBL28133552 | 0.77 | RXRA (0.40) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL11550381 | 0.72 | GMNN (0.48) | — | |
| SCHEMBL11663428 | 0.71 | RXRA (0.40) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL28377655 | 0.71 | RXRA (0.47) | RXRARXRBRXRGPPARGPPARA | |
| SCHEMBL11175136 | 0.70 | GAA (0.40) | NR5A2NR5A1 | |
| SCHEMBL3184779 | 0.70 | SLC13A5 (0.43) | RXRARXRBRXRGHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197433-A1 | Molecular weight modification of thermoplastic polymers | CIBA SPECIALTY CHEMICALS CORP. | 2005-09-08 | — | — | US | disclosed |