SCHEMBL63554

SCHEMBL63554

COc1ccc(OCCOc2ccc(C(C)(C)c3ccc(O)c(C(=O)O)c3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.47
ALDH1A1 P00352 6/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
LMNA P02545 2/20 0.47
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
POLB P06746 4/20 0.45
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
ATM Q13315 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HTT P42858 2/20 0.44
MCL1 Q07820 2/20 0.43
GAA P10253 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
NPC1 O15118 1/20 0.42
APEX1 P27695 1/20 0.42
RAB9A P51151 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27700 0.99 KDM4E (0.46) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL9003467 0.96 KDM4E (0.45) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL9003634 0.96 KDM4E (0.49) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL9003241 0.96 KDM4E (0.49) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL9003277 0.92 KDM4E (0.53) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL9678033 0.92 KDM4E (0.53) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL9677356 0.92 MAPT (0.50) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL8973123 0.91 KDM4E (0.52) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL9676514 0.91 IGF1R (0.46) KDM4EALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL9003368 0.90 CSNK2A1 (0.49) KDM4EALDH1A1SMN1; SMN2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4733081-A1 PRINTING INK FOR HEAT-SENSITIVE RECORDING MEDIA Oji Holdings Corporation (JP) 2026-04-29 EP disclosed
EP-4733080-A1 HEAT-SENSITIVE RECORDING BODY AND METHOD FOR PRODUCING SAME Nippon Paper Industries Co., Ltd. (JP) 2026-04-29 EP disclosed
EP-4056605-B1 THERMOSENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2026-04-22 EP disclosed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
US-12528307-B2 Heat-sensitive recording body Oji Holdings Corporation (JP) 2026-01-20 US disclosed
EP-3954745-B1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) 2026-01-07 EP disclosed
EP-4653202-A1 HEAT-SENSITIVE RECORDING BODY Nippon Paper Industries Co., Ltd. (JP) 2025-11-26 EP disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-20250326242-A1 THERMOSENSITIVE RECORDING MEDIUM Oji Holdings Corporation (JP) 2025-10-23 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
EP-0545442-B1 Microcapsule containing ultraviolet absorber and heat sensitive recording material using the same NEW OJI PAPER CO LTD (JP) 1995-04-05 EP disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed
US-5296440-A Having recording layer containing alkaline pigment and 2,2*-methylenebis(4,6-di-tert-butylphenyl)phosphate or salts KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-03-22 US disclosed
US-5276001-A Color developer comprising salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-01-04 US disclosed
US-5272127-A Heat sensitive recording material using microcapsules containing ultraviolet absorber KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-12-21 US disclosed
EP-0545442-A1 Microcapsule containing ultraviolet absorber and heat sensitive recording material using the same NEW OJI PAPER CO., LTD. (JP) 1993-06-09 EP disclosed
US-5212145-A Containing an ethyleneimine derivative as a preservability improving agent for record images KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-05-18 US disclosed
EP-0506967-A1 THERMAL RECORDING MEDIUM NEW OJI PAPER CO., LTD. (JP) 1992-10-07 EP disclosed
US-5096872-A Colorless basic dye reacts with salicylic acid derivative to form colored image, paper KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-03-17 US disclosed
EP-0424914-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1991-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB KDM4E 3963/4885ALDH1A1 3835/4885SMN1; SMN2 2298/4885
US-12528307-B2 Heat-sensitive recording body LRBA, ARSA, HSPA4L KDM4E 4447/4885ALDH1A1 130/4885SMN1; SMN2 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.