Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18300010 | 0.81 | EPAS1 (0.41) | EPAS1VEGFAABCC8KCNJ11ALDH1A1 | |
| SCHEMBL1340438 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HIF1AVCAM1TDP1ATM | |
| SCHEMBL29860351 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HIF1AVCAM1TDP1ATM | |
| SCHEMBL102571 | 0.78 | EPAS1 (0.42) | EPAS1VEGFAABCC8KCNJ11ALDH1A1 | |
| SCHEMBL31522139 | 0.78 | EPAS1 (0.39) | EPAS1VEGFAABCC8KCNJ11ALDH1A1 | |
| SCHEMBL972079 | 0.77 | ALDH1A1 (0.41) | EPAS1VEGFAABCC8KCNJ11ALDH1A1 | |
| SCHEMBL7513494 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HIF1AVCAM1TDP1ATM | |
| SCHEMBL5316312 | 0.74 | EPAS1 (0.44) | EPAS1VEGFAABCC8KCNJ11ALDH1A1 | |
| SCHEMBL30924883 | 0.74 | TDP1 (0.50) | ALDH1A1HIF1AVCAM1TDP1ATM | |
| SCHEMBL825499 | 0.74 | TDP1 (0.50) | ALDH1A1HIF1AVCAM1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282812-A1 | Inhibitors of cholesteryl ester transfer protein | ARRAY BIOPHARMA INC. | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282812-A1 | Inhibitors of cholesteryl ester transfer protein | CETP, LCAT, MTTP | EPAS1 1316/4885VEGFA 3911/4885ABCC8 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.