SCHEMBL6355919

SCHEMBL6355919

CC(=O)NC1CCCN1NC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 3/20 0.34
EPHX2 P34913 2/20 0.33
EPHX1 P07099 1/20 0.33
ATM Q13315 2/20 0.32
FAP Q12884 3/20 0.32
PREP P48147 2/20 0.32
DPP4 P27487 1/20 0.32
PSEN1 P49768 3/20 0.31
PSEN2 P49810 3/20 0.31
APH1B Q8WW43 3/20 0.31
NCSTN Q92542 3/20 0.31
APH1A Q96BI3 3/20 0.31
PSENEN Q9NZ42 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14076271 0.76 CA1 (0.40) CA1CA2CA12CA9ALDH1A1
SCHEMBL2725761 0.74 CYP3A4 (0.31) ALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL29031251 0.73 CYP3A4 (0.31) ALDH1A1KDM4E
SCHEMBL13458799 0.73 L3MBTL1 (0.50) ALDH1A1FAPPREPDPP4
Ammonia Solution, Strong SCHEMBL29186497 0.73 CYP3A4 (0.31) ALDH1A1KDM4E
SCHEMBL9936383 0.73 L3MBTL1 (0.35) KDM4EEPHX2
SCHEMBL4629917 0.72 CA1 (0.41) CA1CA2CA12CA9ALDH1A1
SCHEMBL4630036 0.72 CHRM2 (0.37) PREPDPP4
SCHEMBL31282858 0.72 CA12 (0.32) CA1CA2CA12CA9
SCHEMBL10520187 0.71 HTT (0.37) CA1CA2CA12CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005121081-A1 METHOD FOR PRODUCING ACETAMIDOPYRROLIDINE DERIVATIVE AND INTERMEDIATE COMPOUND THEREOF TEIJIN PHARMA LIMITED (JP) 2005-12-22 WO disclosed
EP-1377264-A1 DYEING COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A CATIONIC AZO-DYE L'OREAL (FR) 2004-01-07 EP disclosed
WO-2002078659-A1 DYEING COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A CATIONIC AZO-DYE L'OREAL (FR) 2002-10-10 WO disclosed