Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28180724 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL8173198 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL7749461 | 0.90 | ALDH1A1 (0.33) | ALDH1A1HRH3MGLLCYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL691818 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL2831788 | 0.90 | ALDH1A1 (0.33) | ALDH1A1HRH3MGLLCYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL1131241 | 0.90 | ALDH1A1 (0.33) | ALDH1A1HRH3MGLLCYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL7686691 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL9694497 | 0.90 | ALDH1A1 (0.33) | ALDH1A1HRH3MGLLCYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL20483701 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL27951711 | 0.90 | ALDH1A1 (0.33) | ALDH1A1HRH3MGLLCYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090383-A1 | Metal complex compositions and their use as catalysts to produce polydienes | THIELE SVEN K (DE) | 2005-04-28 | — | — | US | claimed |
| CN-1568332-A | Metal complex compositions and their use as catalysts to produce polydienes | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-01-19 | — | — | CN | claimed |
| EP-1436332-A2 | METAL COMPLEX COMPOSITIONS AND THEIR USE AS CATALYSTS TO PRODUCE POLYDIENES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003033545-A2 | METAL COMPLEX COMPOSITIONS AND THEIR USE AS CATALYSTS TO PRODUCE POLYDIENES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-04-24 | — | — | WO | claimed |
| US-20050090383-A1 | Metal complex compositions and their use as catalysts to produce polydienes | THIELE SVEN K (DE) | 2005-04-28 | — | — | US | disclosed |
| CN-1568332-A | Metal complex compositions and their use as catalysts to produce polydienes | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-01-19 | — | — | CN | disclosed |
| EP-1436332-A2 | METAL COMPLEX COMPOSITIONS AND THEIR USE AS CATALYSTS TO PRODUCE POLYDIENES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033545-A2 | METAL COMPLEX COMPOSITIONS AND THEIR USE AS CATALYSTS TO PRODUCE POLYDIENES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-04-24 | — | — | WO | disclosed |