Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 4/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10169075 | 1.00 | KMT2A (0.49) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL6348276 | 0.98 | KMT2A (0.49) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL10169311 | 0.98 | KMT2A (0.49) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL31370443 | 0.89 | KMT2A (0.53) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL31369649 | 0.89 | KMT2A (0.53) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL31370345 | 0.89 | KMT2A (0.53) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL31370149 | 0.89 | KMT2A (0.53) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL31369977 | 0.86 | KMT2A (0.53) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL31369639 | 0.86 | KMT2A (0.53) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL14368653 | 0.86 | KMT2A (0.49) | KMT2AEPHX2CASP3FABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-01-26 | — | — | US | disclosed |
| US-7858737-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |
| US-7858737-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |
| US-6958384-B2 | Polypeptides containing γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-10-25 | — | — | US | disclosed |
| US-20030211999-A1 | Polypeptides containing gamma-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | DNPEP, PRKCSH, YWHAZ | KMT2A 3597/4885EPHX2 2808/4885CASP3 3540/4885 |
| US-20030211999-A1 | Polypeptides containing gamma-amino acids | PEPD, DNPEP, ANPEP | KMT2A 3264/4885EPHX2 3315/4885CASP3 1243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.