PRKCSH

Glucosidase 2 subunit beta · P14314 · PRKCSH on Sugi Atlas →

0 patent compounds predicted against PRKCSH, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PRKCSH by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of a Basal/Pre-Meal Insulin Strategy (Detemir/Aspart) on Insulin Secretion and Action in Type 2 Diabetes PHASE4COMPLETED
Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity PHASE4COMPLETED
Adding Exenatide to Insulin Therapy for Patients With Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease PHASE4COMPLETED
Metformin Induces a Dietary Restriction-like State in Human PHASE4UNKNOWN
Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus. PHASE3COMPLETED
Efficacy Study of Pioglitazone Compared to Glimepiride on Coronary Atherosclerotic Disease Progression in Subjects With Type 2 Diabetes Mellitus PHASE3COMPLETED
Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals PHASE1/PHASE2COMPLETED
Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old PHASE2ACTIVE_NOT_RECRUITING
Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism. PHASE1COMPLETED
Acute Effect of HP-211 (Axulin) on Blood Glucose and Serum Insulin Responses in Healthy Lean and Overweight Humans PHASE1COMPLETED
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome nanCOMPLETED
Effect of Age on Glucose and Lipid Metabolism nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
Duality of Lipids: the Athlete's Paradox nanCOMPLETED
Delineation of the Role of Glucagon-like Peptide-1 Signalling in Relation to Increased Carbohydrate Content in the Distal Small Intestines nanCOMPLETED
Free Fatty Acid Induced Insulin Resistance nanCOMPLETED
Intravenous Terbutaline in Severe Status Asthmaticus nanUNKNOWN
Molecular Mechanisms of Exercise Benefits to Insulin Resistant People nanCOMPLETED
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation nanCOMPLETED
Rare Glycogen Storage Diseases Natural History Study nanRECRUITING
Effect of an Polyphenolic Beverage in Healthy Volunteers nanACTIVE_NOT_RECRUITING
Specificities of Atypical Non AutoImmune Diabetes (ANAID) in the French West Indies nanNOT_YET_RECRUITING
Effects of Chronic Dietary Exposure to Branched Chain Amino Acids nanCOMPLETED
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle nanCOMPLETED
Gene Expression in Obesity and Insulin Resistance nanCOMPLETED
PDE3B in Metabolic Regulation nanENROLLING_BY_INVITATION
Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH nanCOMPLETED
Novel Inhibitors of Lipolysis in the Treatment of Lipid a Glucose Metabolism in Obstructive Sleep Apnea Syndrome nanUNKNOWN
Genetic and Environmental Determinants of Triglycerides (GOLDN) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PRKCSH binder may also engage these)

ProteinNameSimilarity
Q28034 1.000 Q28034 →
O08795 1.000 O08795 →
Q28056 0.984 Q28056 →
ASPH Aspartyl/asparaginyl beta-hydroxylase 0.983 landscape →
Q60432 0.982 Q60432 →
O61307 0.982 O61307 →
Q58CP9 0.982 Q58CP9 →
P52194 0.981 P52194 →
O18738 0.981 O18738 →
CANX Calnexin 0.980 landscape →
P10493 0.980 P10493 →
Q9USH8 0.980 Q9USH8 →
P48193 0.980 P48193 →
P84903 0.979 P84903 →
P34652 0.979 P34652 →
STIM1 Stromal interaction molecule 1 0.979 landscape →
J9VLH0 0.979 J9VLH0 →
P35564 0.979 P35564 →
HYOU1 Hypoxia up-regulated protein 1 0.979 landscape →
G5ED46 0.979 G5ED46 →
Q8BSY0 0.978 Q8BSY0 →
Q10651 0.978 Q10651 →
P08478 0.978 P08478 →
NFKB1 Nuclear factor NF-kappa-B p105 subunit 0.978 landscape →
Q6ZPS6 0.978 Q6ZPS6 →
P36581 0.978 P36581 →
Q9FM96 0.978 Q9FM96 →
P10731 0.978 P10731 →
Q149L6 0.978 Q149L6 →
Q9ERA6 0.977 Q9ERA6 →