SCHEMBL6356302

SCHEMBL6356302

COc1cnc2c(ccc3cccnc32)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.62
CCR8 P51685 3/20 0.62
CCR5 P51681 2/20 0.62
TDP1 Q9NUW8 3/20 0.55
HSP90AA1 P07900 3/20 0.55
KDM4E B2RXH2 2/20 0.55
GMNN O75496 1/20 0.55
LMNA P02545 1/20 0.55
TP53 P04637 1/20 0.55
MMP2 P08253 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
MAPT P10636 1/20 0.55
MMP9 P14780 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
NFKB1 P19838 1/20 0.55
MMP8 P22894 1/20 0.55
THPO P40225 1/20 0.55
MTOR P42345 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30492598 1.00 CCR1 (0.62) CCR1CCR8CCR5TDP1HSP90AA1
SCHEMBL6347577 0.87 RELA (0.52) CCR1CCR8CCR5CYP3A4CYP2D6
SCHEMBL30492638 0.87 RELA (0.52) CCR1CCR8CCR5CYP3A4CYP2D6
SCHEMBL13898402 0.83 CCR1 (0.58) CCR1CCR8CCR5TDP1HSP90AA1
SCHEMBL5012780 0.82 CYP1A2 (0.47) TDP1HSP90AA1KDM4ESLC40A1KMT2A
SCHEMBL14437861 0.81 CCR1 (0.56) CCR1CCR8CCR5TDP1HSP90AA1
SCHEMBL1408873 0.79 CYP1A2 (0.50) TDP1TP53CYP3A4CYP2D6MAPT
SCHEMBL21809375 0.79 CCR1 (0.53) CCR1CCR8CCR5TDP1HSP90AA1
SCHEMBL25687216 0.79 CCR1 (0.70) CCR1CCR8CCR5KDM4ECYP3A4
SCHEMBL196644 0.78 RELA (0.41) CCR1CCR8CCR5SLC40A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-111718381-A Osmium metal organic compound containing polypyridine ligand and preparation method and application thereof 荆楚理工学院 2020-09-29 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
CN-111518145-B Cyano-bridged metal organic compound with intramolecular magnetic transformation and preparation method and application thereof 荆楚理工学院 2023-06-20 CN disclosed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US disclosed
CN-111718381-A Osmium metal organic compound containing polypyridine ligand and preparation method and application thereof 荆楚理工学院 2020-09-29 CN disclosed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN disclosed
US-6929873-B2 Electroluminescent device using metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-08-16 US disclosed
US-20040013905-A1 Electroluminescent device using metal coordination compound CANON KABUSHIKI KAISHA (JP) 2004-01-22 US disclosed