SCHEMBL196644

SCHEMBL196644

COc1cnc2c(ccc3c(OC)ccnc32)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.41
SLC40A1 Q9NP59 2/20 0.40
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38
NPC1 O15118 2/20 0.38
FGFR2 P21802 1/20 0.37
CCR1 P32246 3/20 0.37
CCR5 P51681 3/20 0.37
CCR8 P51685 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
AGTR1 P30556 1/20 0.37
RAB9A P51151 2/20 0.36
GAK O14976 1/20 0.36
RIPK2 O43353 1/20 0.36
COQ8A Q8NI60 1/20 0.36
NLK Q9UBE8 1/20 0.36
TRPA1 O75762 1/20 0.36
AURKA O14965 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5931340 0.94 RELA (0.41) RELASLC40A1PDGFRBPDGFRANPC1
SCHEMBL6347577 0.82 RELA (0.52) RELANPC1CCR1CCR5CCR8
SCHEMBL30492638 0.82 RELA (0.52) RELANPC1CCR1CCR5CCR8
SCHEMBL185654 0.80 CCR1 (0.50) SLC40A1PDGFRBPDGFRANPC1CCR1
SCHEMBL30492598 0.78 CCR1 (0.62) RELASLC40A1NPC1CCR1CCR5
SCHEMBL30492645 0.78 CCR1 (0.62) SLC40A1PDGFRBPDGFRANPC1CCR1
SCHEMBL6356302 0.78 CCR1 (0.62) RELASLC40A1NPC1CCR1CCR5
SCHEMBL10505657 0.78 CCR1 (0.62) SLC40A1PDGFRBPDGFRANPC1CCR1
Hydrochloric Acid SCHEMBL5931133 0.74 ATR (0.33) CCR1CCR5CCR8L3MBTL1MEN1
SCHEMBL25687216 0.74 CCR1 (0.70) RELANPC1CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180128767-A1 Small Volume In Vitro Analyte Sensor ABBOTT DIABETES CARE INC. (US) 2018-05-10 US disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
US-20160334356-A1 Small Volume In Vitro Analyte Sensor THERASENSE, INC. 2016-11-17 US disclosed
US-20160235350-A1 Integrated Sample Acquisition and Analyte Measurement Device THERASENSE, INC. 2016-08-18 US disclosed
US-9341591-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-05-17 US disclosed
US-9316609-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-04-19 US disclosed
US-9291592-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-03-22 US disclosed
US-9271669-B2 Method for integrated sample acquisition and analyte measurement device ABBOTT DIABETES CARE INC. (US) 2016-03-01 US disclosed
US-9234863-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-01-12 US disclosed
US-20030199744-A1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. (US) 2003-10-23 US disclosed
US-6618934-B1 Method of manufacturing small volume in vitro analyte sensor THERASENSE, INC. 2003-09-16 US disclosed
US-6592745-B1 Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care THERASENSE, INC. 2003-07-15 US disclosed
US-6591125-B1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. 2003-07-08 US disclosed
US-6461496-B1 BLOOD GLUCOSE THERASENSE, INC. 2002-10-08 US disclosed
US-6338790-B1 DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE THERASENSE, INC. 2002-01-15 US disclosed
CN-1322254-A Small volume in vitro analytical sensor containing diffusible or non-leachable redox mediator THERASENSE INC (US) 2001-11-14 CN disclosed
US-6299757-B1 ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS THERASENSE, INC. 2001-10-09 US disclosed
EP-1119637-A1 SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR Therasense, Inc. (US) 2001-08-01 EP disclosed
WO-2000020626-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE, INC. (US) 2000-04-13 WO disclosed