Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.48 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6356475 | 1.00 | MAPK1 (0.53) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL7348151 | 0.85 | MAPK1 (0.58) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL7345520 | 0.85 | MAPK1 (0.58) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL26014304 | 0.81 | KMT2A (0.57) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL7350410 | 0.81 | MAPK1 (0.54) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL18332505 | 0.81 | MAPK1 (0.54) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL7350419 | 0.81 | MAPK1 (0.54) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL10832584 | 0.81 | MAPK1 (0.54) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL1488576 | 0.79 | MAPK1 (0.53) | MAPK1CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL8540424 | 0.79 | MAPK1 (0.53) | MAPK1CYP3A4KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187274-A1 | One pot synthesis of 2-oxazolidinone derivatives | PATEL RAJNIKANT (GB) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187274-A1 | One pot synthesis of 2-oxazolidinone derivatives | AZI2, INTS6, NISCH | MAPK1 1600/4885CYP3A4 209/4885KMT2A 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.