SCHEMBL26014304

SCHEMBL26014304

OC[C@@H](Cc1ccccc1)NP

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 1/20 0.57
MEN1 O00255 1/20 0.57
MAPT P10636 1/20 0.57
MAPK1 P28482 2/20 0.54
CYP3A4 P08684 1/20 0.54
TRPA1 O75762 1/20 0.50
EPHX1 P07099 2/20 0.48
ROCK2 O75116 3/20 0.45
ROCK1 Q13464 3/20 0.45
RPS6KA5 O75582 1/20 0.45
RPS6KA4 O75676 1/20 0.45
PRKACA P17612 1/20 0.45
GSK3A P49840 1/20 0.45
GSK3B P49841 1/20 0.45
IRAK1 P51617 1/20 0.45
PRKX P51817 1/20 0.45
PRKG1 Q13976 1/20 0.45
PKN2 Q16513 1/20 0.45
CLK4 Q9HAZ1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7345520 0.86 MAPK1 (0.58) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL7348151 0.86 MAPK1 (0.58) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL14074601 0.86 KDM4E (0.45) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL10832584 0.83 MAPK1 (0.54) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL7350410 0.83 MAPK1 (0.54) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL7350419 0.83 MAPK1 (0.54) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL18332505 0.83 MAPK1 (0.54) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL1488576 0.81 MAPK1 (0.53) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL8540424 0.81 MAPK1 (0.53) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL6356482 0.81 MAPK1 (0.53) KMT2AKDM4EMEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242476-A1 A PROCESS FOR THE PURIFICATION OF (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE FLAMMA SPA (IT) 2023-08-03 US disclosed
US-20230242476-A1 A PROCESS FOR THE PURIFICATION OF (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE FLAMMA SPA (IT) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242476-A1 A PROCESS FOR THE PURIFICATION OF (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE PHYKPL, BPHL, DNPEP KMT2A 273/4885KDM4E 179/4885MEN1 3689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.