Fluprostenol

Fluprostenol

SCHEMBL635658

O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COc2cccc(C(F)(F)F)c2)[C@H](O)C[C@@H]1O.[NaH]

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGFR P43088 16/20 0.98
PTGER3 P43115 5/20 0.98
ABCC4 O15439 2/20 0.80
ABCB11 O95342 1/20 0.80
TBXA2R P21731 3/20 0.77
PTGER1 P34995 2/20 0.77
THRB P10828 1/20 0.77
PTGER2 P43116 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluprostenol SCHEMBL10015915 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL230607 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL16414486 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL24342073 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL13260302 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL24342036 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL6750653 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL2744986 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL20860290 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R
Fluprostenol SCHEMBL16414497 0.99 PTGFR (1.00) PTGFRPTGER3ABCC4ABCB11TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-4202880-A SUSTAINED RELEASE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-05-13 US claimed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
US-20250339367-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
US-12403090-B2 Oral film compositions and dosage forms having precise active dissolution profiles AQUESTIVE THERAPEUTICS, INC. (US) 2025-09-02 US disclosed
US-20250255780-A1 SYSTEM AND METHOD FOR MAKING PERSONALIZED INDIVIDUAL UNIT DOSES CONTAINING PHARMACEUTICAL ACTIVES AQUESTIVE THERAPEUTICS, INC. (US) 2025-08-14 US disclosed
US-12310922-B2 System and method for making personalized individual unit doses containing pharmaceutical actives AQUESTIVE THERAPEUTICS, INC. (US) 2025-05-27 US disclosed
US-5795909-A ANTICARCINOGENIC AND ANTITUMOR AGENTS; BREAST, COLON, OVARIANCANCERS NEUROMEDICA, INC. (US) 1998-08-18 US disclosed
WO-1997044063-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES NEUROMEDICA, INC. (US) 1997-11-27 WO disclosed
EP-0245858-B1 ADHESIVE FOR PERCUTANEOUS ADMINISTRATION TAKIRON CO. LTD. (JP) 1992-07-29 EP disclosed
US-4997656-A Layer containing heat-and water-sensitive amphiphilic polymer and biologically active agent TAKIRON CO., LTD. (JP) 1991-03-05 US disclosed
EP-0245858-A2 Adhesive for percutaneous administration TAKIRON CO. LTD. (JP) 1987-11-19 EP disclosed
US-4235988-A HYDROPHILIC BLOCK POLYOXYALKYLENE-POLYURETHANE COPOLYMER CARRIER WHICH PERMITS SUSTAINED RELEASE OF THE DRUG IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-11-25 US disclosed
US-4202880-A SUSTAINED RELEASE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A PTGFR 3278/4885PTGER3 3331/4885ABCC4 912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.